You are viewing an incomplete version of our website. Please click to reload the website as full version.

Keratin 2 (KRT2) (AA 2-23), (N-Term) antibody

Details for Product No. ABIN126065, Supplier: Log in to see
Antigen
  • KRT2
  • krt2a
  • CK-2e
  • K2e
  • KRT2A
  • KRT2E
  • KRTE
  • BB005427
  • Krt2-17
  • Krt2-2
  • Krt2e
  • Kb2
  • K2E
Epitope
AA 2-23, N-Term
9
7
6
6
5
3
2
1
1
Reactivity
Cow (Bovine), Human, Mouse (Murine)
32
16
8
3
3
1
1
Host
Guinea Pig
30
15
2
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
36
19
15
12
12
6
5
2
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Immunogen Synthetic peptide (N-terminal aa 2-23) of human keratin K2.
Purification Serum
Alternative Name Cytokeratin 2e (KRT2 Antibody Abstract)
Background Keratins are the major gene product of keratinocytes and form the intermediate filament cytoskeletal network in these cells. In cells of the upper spinous layer, KRT2E and KRT9 are expressed. Although the expression of KRT9 is limited to palmoplantar epidermis, KRT2E is expressed not only in this tissue but also in other regions, notably the epidermis covering the knee, thigh, and groin. It is not known whether these keratins simply replace their respective type I or type II counterpart in the preexisting KRT1/KRT10 network or dimerize with another, as yet undiscovered keratin partner.Synonyms: CK2e, Cytokeratin-2e, K2e, KRT2, KRT2A, KRT2E, Keratin, Keratin-2, type II cytoskeletal 2 epidermal
Gene ID 9606
UniProt P35908
Research Area Extracellular Matrix
Application Notes Immunoblotting: 1: 5000 - 1: 10 000, ECL method. Immunohistochemistry on frozen sections: 1: 200. Immunohistochemistry on paraffin sections: 1: 100, 1 h at RT. Immunohistochemistry on cytological material.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Swensson, Langbein, McMillan et al.: "Specialized keratin expression pattern in human ridged skin as an adaptation to high physical stress." in: The British journal of dermatology, Vol. 139, Issue 5, pp. 767-75, 1999 (PubMed).

Collin, Moll, Kubicka et al.: "Characterization of human cytokeratin 2, an epidermal cytoskeletal protein synthesized late during differentiation." in: Experimental cell research, Vol. 202, Issue 1, pp. 132-41, 1992 (PubMed).