Keratin 7 (KRT7) antibody
| Antigen |
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| Synonyms |
K7, CK7, SCL, K2C7, MGC3625, MGC129731, Krt2-7, MGC11625, D15Wsu77e, KRT7, MGC137771 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Human (132), Rat (Rattus) (38), Mouse (Murine) (34), Dog (Canine) (9), Pig (Porcine) (9), Cow (Bovine) (8), Hamster (6), Cat (Feline) (5), Sheep (Ovine) (4), Zebrafish (Danio rerio) (3), Chicken (1), Goat (1), Rabbit (1)
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Conjugate
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FITC (9), Biotin (5), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2)
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Application
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 Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Western Blotting (WB) (95), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (58), Immunofluorescence (IF) (54), Immunohistochemistry (IHC) (44), ELISA (43), Immunocytochemistry (ICC) (24), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), Flow Cytometry (FACS) (18), Immunoprecipitation (IP) (18), Immunohistochemistry (Fixed) (IHC (fx)) (13), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Immunoelectron Microscopy (IEM) (2)
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| Catalog no. |
ABIN126067 |
| Quantity |
0.1 mL |
| Price |
495.00 $ Plus shipping costs $45.00
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| Shipping to |
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| Availability |
Will be delivered in 6 to 8 Business Days |
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Alternative name
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Cytokeratin 7
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UniProt
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P08729
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Immunogen
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Synthetic peptide (C-SAGPGLLKAYSIRT) of human keratin K7 (formerly also designatedcytokeratin 7), coupled to KLH.
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Cross-Reactivity
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Human
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Description
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Cytokeratin 7 is a 54kD intermediate filament protein found in a variety ofglandularepithelia. Cytokeratin 7 has been found in columnar and glandular epithelium ofthe lung, cervix, breast, bile ducts and larger collecting ducts of the kidney. It is present inthe transitional epithelium of bladder as well as ovarian and lungepithelia, andoccasionally staining of blood vessel cell walls, particularly endothelial cells, may beobserved. However, Cytokeratin 7 is not expressed by epithelial cells of thegastrointestinal tract, colon or prostate. Keratin 7 is often co expressed with keratin 19.
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Characteristics
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Synonyms: KRT7, KRT-7, SCL, CK-7, CK7, Keratin-7, K7, K-7, Sarcolectin, Keratin type II cytoskeletal 7
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Application Notes
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Western blotting: 1: 3000 (ECL). Immunohistochemistry on frozen (1: 200) and paraffin-embedded (1/100) sections (aftermicrowave treatment). Cytological material. Incubation time: 1 h at RT, extended with paraffin sections. Positive control: Glandular epithelia (e. g. sweat glands, sebaceous glands), Merkel cells. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Purification
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Serum
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Storage
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Store at 2-8°C. Shelf life: one year from despatch.
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Research Area
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Signaling, Cytoskeleton, Cytokeratins, Extracellular Matrix
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Restrictions
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For Research Use only
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Ramaekers, van Niekerk, Poels et al.: "Use of monoclonal antibodies to keratin 7 in the differential diagnosis of adenocarcinomas." in: The American journal of pathology, Vol. 136, Issue 3, pp. 641-55, 1990 (PubMed).
Moll, Franke, Schiller et al.: "The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells." in: Cell, Vol. 31, Issue 1, pp. 11-24, 1983 (PubMed).
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Alternatives for antigen "Keratin 7 (KRT7)", type "Antibodies"
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Hosts
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Rabbit (85), Mouse (76), Goat (1), Guinea Pig (1)
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Reactivities
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Human (132), Rat (Rattus) (38), Mouse (Murine) (34), Dog (Canine) (9), Pig (Porcine) (9), Cow (Bovine) (8), Hamster (6), Cat (Feline) (5), Sheep (Ovine) (4), Zebrafish (Danio rerio) (3), Chicken (1), Goat (1), Rabbit (1)
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Applications
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Western Blotting (WB) (95), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (58), Immunofluorescence (IF) (54), Immunohistochemistry (IHC) (44), ELISA (43), Immunocytochemistry (ICC) (24), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), Flow Cytometry (FACS) (18), Immunoprecipitation (IP) (18), Immunohistochemistry (Fixed) (IHC (fx)) (13), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Immunoelectron Microscopy (IEM) (2)
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Conjugates
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FITC (9), Biotin (5), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2)
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Epitopes
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Middle Region (36), N-Term (6), C-Term (3), Internal Region (1), N-Term,AA 110-139 (1)
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