You are viewing an incomplete version of our website. Please click to reload the website as full version.

Keratin 13 (KRT13) antibody

Details for Product No. ABIN126069, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms krt13, CK13, K13, Ka13, Krt-1.13, Krt1-13, ck13, k13
Human, Mouse (Murine)
(140), (37), (34), (4), (3), (3), (2), (2), (1), (1), (1)
Guinea Pig
(63), (62), (19), (2)
(2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(112), (51), (48), (38), (30), (23), (11), (9), (8), (4), (3), (1), (1), (1)
Pubmed 1 reference available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 0.1 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Synthetic peptide (TTTSSASVTTTSNA-C) of Human keratin K13 (formerly also designated cytokeratin 13), coupled to KLH.
Specificity This antibody recognizes Acidic Human keratin K13 (Mr 55 000). Excellent marker to discriminate non-cornified squamous epithelia (esophagus, vagina, gingival) from those of different origin. Negative on foot sole, scalp. Tumors Specifically Detected: Several squamous cell carcinomas, e.g. cervix carcinoma, transitional cell carcinoma of the bladder, craniopharyngioma.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse.
Purification Serum
Alternative Name Cytokeratin 13 (KRT13 Antibody Abstract)
Background Cytokeratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.Synonyms: CK-13, CK13, K13, KRT-13, KRT13, Keratin type I cytoskeletal 13, Keratin-13
Gene ID 3860
NCBI Accession NP_002265
UniProt P13646
Research Area Signaling, Cytoskeleton, Extracellular Matrix
Application Notes Immunoblotting: 1: 3000, ECL method. Immunohistochemistry on frozen sections: 1: 200. Immunohistochemistry on paraffin sections: 1: 100, 1h at RT, after microwave treatment. Immunohistochemistry on cytological material. Positive Control: Squamous epithelium of esophagus, gingival, palate, vagina (staining allof the suprabasal layers).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer 0.09 % Sodium Azide 0.9 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice This product is photosensitive and should be protected from light
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C Prior to and following reconstitution . DO NOT FREEZE!
Background publications Moll, Franke, Schiller et al.: "The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells." in: Cell, Vol. 31, Issue 1, pp. 11-24, 1983 (PubMed).

Catalog No. ABIN126069
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)