Keratin 38 (KRT38) antibody

Details for Product No. ABIN126082
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Antigen
Synonyms HA8, hHa8, KRTHA8, KRT37
Reactivity
Human, Mouse (Murine)
(6)
Host
Guinea Pig
(4), (2)
Clonality
Polyclonal
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(6), (1), (1)
Pubmed 2 references available
Quantity 0.1 mL
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Catalog No. ABIN126082
500.50 $
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Immunogen Synthetic peptide of human acidic hair (trichocytic) keratin K38 (formerly also designated keratin hHa8, TTC GPT CGA STT GSR F), coupled to KLH.
Specificity The antiserum stains specifically human hair keratin K38 expressed starting from the middle cortex. The staining in the middle cortex appears highly heterogeneous.
Purification Serum
Alternative Name Keratin-38 (KRT38)
Background Alternate names: HHA8, HKA8, Hair keratin, K38, KRT38, KRTHA8, Keratin, Keratin 38, Keratin-38, Keratin38, type I Ha8, type I cuticular Ha8
Gene ID 8687
NCBI Accession NP_006762
UniProt O76015
Application Notes Immunoblotting: 1 : 2,000, ECL method. Immunohistochemistry on frozen sections: 1: 200, 1h at RT. NOTE: For enhancement of cortex staining preincubate fixed sections with 0.1 Triton X-100(in PBS) for 1 - 5 min prior to first antibody incubation step. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8°C.
Expiry Date 12 months
Background publications Langbein, Rogers, Winter et al.: "The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle." in: The Journal of biological chemistry, Vol. 274, Issue 28, pp. 19874-84, 1999 (PubMed).

Langbein, Spring, Rogers et al.: "Hair keratins and hair follicle-specific epithelial keratins." in: Methods in cell biology, Vol. 78, pp. 413-51, 2005 (PubMed).

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