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Peripheral-Type Benzodiazepine Receptor (TSPO) antibody

Antigen

Peripheral-Type Benzodiazepine Receptor (TSPO)

Synonyms DBI, IBP, MBR, PBR, BZRP, PKBS, PTBR, mDRC, pk18, Bzrp, Tspo1, Ptbzr, PTBZR02, RATPTBZR02, LOC732875, LOC100136652, LOC100280949
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)

Application
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Catalog no. ABIN126991
Quantity 0.1 mg  (0.2 mg/ml)  (Variants)
Price 340.00 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information

Characteristics Synonyms: MBR, Translocator protein, Peripheral-type benzodiazepine receptor, PKBS, PBR,Mitochondrial benzodiazepine receptor
Alternative name TSPO / BZRP
Swiss-Prot P30536
Immunogen Synthetic peptide surrounding amino acid 81 of Mouse PBR.
Description PBR (Peripheral-type Benzodiazepine Receptor) is a ubiquitous protein (18 kDa) found inmost steroidogenic tissues. It is located primarily in the outer mitochondrial membrane ofsteroid-producing tissues and is found in association with a 34 kDa voltage-dependentanion channel protein (VDAC). PBR is involved in the regulation of cholesterol transportfrom the outer to the inner mitochondrial membrane. It is thought to be part of themitochondrial permeability transition pore (PT) and to be involved in apoptosis.
Specificity This antibody detects PBR. Species: Human, Mouse and Rat. Others not tested. Add. Information: Blocking peptide (ABIN126990) is available separately.

Application Details

Application Notes Western Blot: 0.5-4 µg/ml. Immunohistochemistry on Frozen and Paraffin Sections: 10-20 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 0.2 mg/ml
Buffer PBS, pH 7.2 containing 30% Glycerol, 0.5% BSA as stabilizer and 0.01%Thimerosal as preservative.
Storage Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -20°C to-70°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Peripheral-Type Benzodiazepine Receptor (TSPO)", type "Antibodies"
Hosts Rabbit (3), Goat (2)
Reactivities Human (4), Mouse (Murine) (1)
Applications Western Blotting (WB) (4), ELISA (2), Enzyme Immunoassay (EIA) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunohistochemistry (IHC) (1)
Epitopes C-Term (1)