Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) antibody

Antigen: Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2)

Synonyms: p97, AAG1, DAP5, NAT1, FLJ41344, EIF4G2, NAT1B, eif4g2, hm:zeh1307, wu:fa14h01, wu:fb44h01, wu:fb59c06, wu:fc21b05, DKFZp459D102

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN127065

Additional Information

Characteristics: Synonyms: eIF-4-gamma 2, p97, AAG1, NAT1, FLJ41344, Death-associated protein 5, Eukaryotictranslation initiation factor 4 gamma 2

Alternative name: EIF4G2 / DAP5

Swiss-Prot: P78344

Description: Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequencehomology to eukaryotic translation initiation factor 4G (eIF4G). Compared with eIF4G, DAP5lacks the N-terminal region necessary for cap-dependent translation and has a uniqueC-terminal part functioning as a regulator for interferon-gamma induced cell death. Duringapoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions asa cap-independent translation initiation factor responsible for the mediation of its owntranslation during apoptosis.

Specificity: The antibody detects 97 kDa DAP5. It does not cross react with other DAP family membersor with eIF4G. Species: Human, mouse, rat. Others not tested.

Application Details

Application Notes: The antibody can be used for Western blot (at 0.5 - 4 μg/ml). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 0.5 mg/ml

Buffer: Phosphate buffered saline (PBS), pH 7.2, containing 50 % glycerol, 1 %BSA, 0.02 % sodium azide.

Storage: Store at -20 °C. Shelf life: one year from despatch. For longer storage freeze at -70 °C. Avoid repeated freeze/defrost cycles!

Restrictions: For Research Use only