RASA1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB31772
unconjugated
Application Notes
Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry: 10-20 μg/mL. Jurkat cell lysate can be used as a positive control. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
The mammalian proto-oncogene Ras encodes 21 kDa proteins (p21Ras) which exists in either a physiologically quiescent GDP-binding state or a GTPbinding signal-emitting state. Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold. The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity.Synonyms: GAP, RASA, Ras GTPase-activating protein 1, Ras p21 protein activator, p120GAP, p120RASGAP