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MMP13 antibody
MMP13
Reactivity: Human, Mouse, Rat, Rabbit, Cow, Horse
WB, IP, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MMP13 Antibody
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Target
See all MMP13 Antibodies
MMP13
(Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
Reactivity
All reactivities for MMP13 antibodies
Human, Mouse, Rat, Rabbit, Cow, Horse
Host
All hosts for MMP13 antibodies
Rabbit
Clonality
All clonalities for MMP13 antibodies
Polyclonal
Conjugate
All conjugates for MMP13 antibodies
This MMP13 antibody is un-conjugated
Application
All applications for MMP13 antibodies
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
The antibody recognizes the proenzyme (~60 kDa) and the cleaved fragments (34 kDa and 48 kDa) of MMP-13.
Cross-Reactivity (Details)
Species reactivity (expected):Mouse, Rat, Equine (Horse), Rabbit and Bovine. Species reactivity (tested):Human.
Purification
Affinity Chromatography.
Immunogen
Synthetic peptide surrounding amino acid 454 of Rat MMP-13.
Top Product
Discover our top product MMP13 Primary Antibody
Alternatives
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Application Details
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Application Notes
Western blotting (0.5-4 μg/mL) . Immunoprecipitation. Immunohistochemistry (works with Paraffin Embedded Sections). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C/-80 °C
Storage Comment
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
Target Details for MMP13
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Target
MMP13
(Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
Alternative Name
MMP-13 (MMP13 Products )
Synonyms
CLG3 antibody, MANDP1 antibody, Clg antibody, MMP-13 antibody, Mmp1 antibody, cb1034 antibody, mmp13 antibody, gene A antibody, xCol antibody, xcl3 antibody, MMP13 antibody, MGC108008 antibody, matrix metallopeptidase 13 antibody, matrix metallopeptidase 13a antibody, matrix metallopeptidase 13 (collagenase 3) like S homeolog antibody, matrix metallopeptidase 13 (collagenase 3) antibody, matrix metalloproteinase 13 antibody, matrix metallopeptidase 13 (collagenase 3) like L homeolog antibody, MMP13 antibody, Mmp13 antibody, mmp13a antibody, mmp13l.S antibody, mmp13 antibody, LOC100136348 antibody, mmp13l.L antibody
Background
The Matrix Metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen type I, II, III.Synonyms: Collagenase 3, MMP13, Matrix metalloproteinase-13
Gene ID
4322
NCBI Accession
NP_002418
UniProt
P45452
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