BCMA antibody (C-Term)

Catalog No. ABIN127204

Product Details anti-BCMA Antibody

Target: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCMA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Detects 27 kDa human BCMA.

Purification: Affinity purified

Immunogen: Synthetic peptide mapping at the carboxy terminus of human BCMA.

Application Details

Application Notes: Western Blot: 2-6 μg/mL. Immunohistochemistry: 5-20 μg/mL. Human spleen tissue can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for BCMA

Target: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Alternative Name: CD269 / BCMA (TNFRSF17 Products)

Synonyms: TNFRSF17 antibody, BCM antibody, BCMA antibody, CD269 antibody, TNFRSF13A antibody, Tnfrsf13 antibody, Tnfrsf13a antibody, TNF receptor superfamily member 17 antibody, tumor necrosis factor receptor superfamily, member 17 antibody, Tnfrsf17 antibody, TNFRSF17 antibody

Background: BCMA is a recently identified receptor for BAFF. It binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-κB and c-Jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.Synonyms: B-cell maturation protein, BCM, TNFRSF17, Tumor necrosis factor receptor superfamily member 17

Gene ID: 608

NCBI Accession: NP_001183

UniProt: Q02223