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Phospholipase C gamma 2 antibody (C-Term)

PLCG2 Reactivity: Human, Rat, Mouse WB, IHC (p), IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN127211
  • Target See all Phospholipase C gamma 2 (PLCG2) Antibodies
    Phospholipase C gamma 2 (PLCG2)
    Binding Specificity
    • 31
    • 22
    • 16
    • 16
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 130
    • 66
    • 52
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    Human, Rat, Mouse
    Host
    • 124
    • 6
    Rabbit
    Clonality
    • 120
    • 10
    Polyclonal
    Conjugate
    • 59
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Phospholipase C gamma 2 antibody is un-conjugated
    Application
    • 95
    • 40
    • 40
    • 36
    • 35
    • 23
    • 18
    • 18
    • 11
    • 6
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    Specificity
    The antibody recognizes 150 kDa PLCγ2. The antibody does not cross-react with PLCγ1.
    Purification
    Affinity purified
    Immunogen
    Synthetic peptide near the C-terminus of human PLCgamma2.
    Top Product
    Discover our top product PLCG2 Primary Antibody
  • Application Notes
    Western Blot: 1-4 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry: 20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • Target
    Phospholipase C gamma 2 (PLCG2)
    Alternative Name
    PLCG2 (PLCG2 Products)
    Synonyms
    PLCgamma2 antibody, Plcg-2 antibody, APLAID antibody, FCAS3 antibody, phospholipase C, gamma 2 antibody, phospholipase C gamma 2 antibody, phospholipase C, gamma 2 (phosphatidylinositol-specific) antibody, Plcg2 antibody, PLCG2 antibody
    Background
    PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCβ, PLCγ, PLCδ, and PLCε. In response to extracellular stimuli (e.g., hormone, growth factors, neurotransmitters), PLC hydrolizes phosphatidylinositol 4,5-biphosphate (PIP2) into two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PLCγ2 is engaged in antigen-dependent signaling in B-cells and collagen-dependent signaling in platelets.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-2, PLC-IV, PLC-gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, Phospholipase C-gamma-2
    Gene ID
    5336
    NCBI Accession
    NP_002652
    UniProt
    P16885
    Pathways
    RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
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