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DIDO1 antibody (N-Term)
DIDO1
Reactivity: Human, Mouse
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DIDO1 Antibody
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Target
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DIDO1
(Death Inducer-Obliterator 1 (DIDO1))
Binding Specificity
All epitopes for DIDO1 antibodies
N-Term
Reactivity
All reactivities for DIDO1 antibodies
Human, Mouse
Host
All hosts for DIDO1 antibodies
Rabbit
Clonality
All clonalities for DIDO1 antibodies
Polyclonal
Conjugate
All conjugates for DIDO1 antibodies
This DIDO1 antibody is un-conjugated
Application
All applications for DIDO1 antibodies
Western Blotting (WB)
Specificity
The antibody recognizes the 62 kDa Dio-1.
Purification
Protein A affinity purified
Immunogen
Synthetic peptide near the N-terminus of mouse Dio-1.
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Alternatives
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Application Details
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Application Notes
Western Blot: 0.5-4 μg/mL, Jurkat cell lysate and mouse small intestine tissue lysate can beused as positive controls. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0.2 mg/mL
Buffer
PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C/-80 °C
Storage Comment
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
Target Details for DIDO1
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Target
DIDO1
(Death Inducer-Obliterator 1 (DIDO1))
Alternative Name
DIDO1 (DIDO1 Products )
Synonyms
5DI antibody, TXDI1 antibody, BYE1 antibody, C20orf158 antibody, DATF-1 antibody, DATF1 antibody, DIDO2 antibody, DIDO3 antibody, DIO-1 antibody, DIO1 antibody, dJ885L7.8 antibody, 6720461J16Rik antibody, C530043I07 antibody, D130048F08Rik antibody, Datf1 antibody, Dido2 antibody, Dido3 antibody, mKIAA0333 antibody, DIDO1 antibody, datf1l antibody, fi35b04 antibody, wu:fi35b04 antibody, zgc:158157 antibody, DKFZp469J1523 antibody, bye1 antibody, dio1 antibody, datf1 antibody, dido2 antibody, dido3 antibody, dio-1 antibody, iodothyronine deiodinase 1 antibody, death inducer-obliterator 1 antibody, death inducer-obliterator 1 L homeolog antibody, DIO1 antibody, DIDO1 antibody, Dido1 antibody, dido1.L antibody, dido1 antibody
Background
Apoptosis plays an important role in many cellular processes. Dio-1 (Death Inducer-O bliterator-1), a putative transcription factor, has been indicated to function in the onset of apoptosis. Dio-1 expression is upregulated when an apoptosis is detected. It translocates to the nucleus, and activates apoptosis during limb development. Dio-1 expression can be suppressed by caspase inhibitors and Bcl-2 expression.Synonyms: C20orf158, DATF1, Death-inducer obliterator 1, KIAA0333
Gene ID
11083
NCBI Accession
NP_001180298
UniProt
Q9BTC0
Pathways
Hormone Activity
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