Annexin VIII antibody

Catalog No. ABIN127268

Product Details anti-Annexin VIII Antibody

Target: Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin VIII antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: The antibody detects 36 kDa annexin VIII of Human origin. The ~28-30 kDa cleavage fragments can also be detected in Jurkat cell lysate. Blocking peptide is available separately (AP00292CP-N).

Purification: Protein A Affinity Chromatography

Immunogen: Synthetic peptide surrounding amino acid 316 of Human Annexin VIII.

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL, Jurkat cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2 containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for Annexin VIII

Target: Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

Alternative Name: Annexin A8 / ANXA8 (ANXA8 Products)

Synonyms: ANX8 antibody, ANXA8L1 antibody, ANXA8L2 antibody, AI466995 antibody, Anx8 antibody, anx8 antibody, MGC85309 antibody, ANXA8 antibody, annexin A8 antibody, annexin A8 S homeolog antibody, ANXA8 antibody, Anxa8 antibody, anxa8.S antibody, LOC694628 antibody, LOC100052045 antibody

Background: The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain which binds to phospholipids in a Ca2+-dependent manner. Annexin family members have been implicated as regulators of diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. Annexin VIII is preferentially expressed in acute promyelocytic leukemia (APL) cells which may relate its role in hematopoietic cell differentiation.Synonyms: ANX8, Annexin VIII, Annexin-8, VAC-beta, Vascular anticoagulant-beta

Gene ID: 244

NCBI Accession: NP_001035173

UniProt: P13928