SDC4 antibody

Catalog No. ABIN127275

Product Details anti-SDC4 Antibody

Target: SDC4 (Syndecan 4 (SDC4))

Reactivity: Human, Mouse, Rat, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody detects Syndecan-4.

Purification: Protein A purified

Immunogen: Synthetic peptide surrounding amino acid 184 of human Syndecan-4

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 5-10 μg/mL. Immunohistochemistry (Frozen and paraffin sections): 15-25 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA, 0.01 % Thimerosal.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for SDC4

Target: SDC4 (Syndecan 4 (SDC4))

Alternative Name: Syndecan-4 (SDC4) (SDC4 Products)

Synonyms: SYND4 antibody, AA959608 antibody, AW108331 antibody, Synd4 antibody, ryudocan antibody, syndecan-4 antibody, RATRYUDOCA antibody, RYUDOCA antibody, SDC4 antibody, sdc4l antibody, wu:fc47g09 antibody, Syndecan-4 antibody, amphiglycan antibody, syn-4 antibody, syn4 antibody, syndecan 4 antibody, syndecan 4 S homeolog antibody, syndecan 4 L homeolog antibody, SDC4 antibody, Sdc4 antibody, sdc4 antibody, sdc4.S antibody, sdc4.L antibody

Background: Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 is an matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan-1 and Syndecan-3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan-2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.Synonyms: Amphiglycan, Ryudocan core protein, SYND4

Gene ID: 6385

NCBI Accession: NP_002990

UniProt: P31431

Pathways: Glycosaminoglycan Metabolic Process