×
For best experience we recommend to activate Javascript in your browser.
JNK antibody (C-Term)
MAPK8
Reactivity: Human, Mouse, Rat
WB, IHC (p), IP
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-JNK Antibody
(hide)
Target
See all JNK (MAPK8) Antibodies
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
Binding Specificity
All epitopes for JNK antibodies
C-Term
Reactivity
All reactivities for JNK antibodies
Human, Mouse, Rat
Host
All hosts for JNK antibodies
Rabbit
Clonality
All clonalities for JNK antibodies
Polyclonal
Conjugate
All conjugates for JNK antibodies
This JNK antibody is un-conjugated
Application
All applications for JNK antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
Specificity
The antibody detects the 46 kDa JNK1.
Purification
Immunoaffinity Chromatography.
Immunogen
Synthetic peptide mapping to the C-terminus of human JNK-1
Top Product
Discover our top product MAPK8 Primary Antibody
Alternatives
(show)
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (pThr183), (pTyr185) antibody
MAPK8
Reactivity: Human, Mouse, Rat, Dog, Rabbit
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), ICC, IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 201-300) antibody
MAPK8
Reactivity: Human, Mouse, Rat, Chicken, Dog
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
(hide)
Application Notes
Western Blot: 1 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry: 10-20 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
(hide)
Concentration
0.5 mg/mL
Buffer
PBS pH 7.2, containing 50 % Glycerol, 1 % BSA, 0.02 % Thimerosal.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C/-80 °C
Storage Comment
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
Target Details for JNK
(hide)
Target
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
Alternative Name
MAPK8 / JNK1 (MAPK8 Products )
Synonyms
JNK antibody, JNK-46 antibody, JNK1 antibody, JNK1A2 antibody, JNK21B1/2 antibody, PRKM8 antibody, SAPK1 antibody, SAPK1c antibody, AI849689 antibody, Prkm8 antibody, BSK antibody, BSK/DJNK antibody, Bsk antibody, CG5680 antibody, D-JNK antibody, D-junk antibody, DBSK/JNK antibody, DJNK antibody, DJNK/bsk antibody, Dmel\\CG5680 antibody, JNK/SAPK antibody, Jnk antibody, Junk antibody, SAPKa antibody, c-Jun antibody, dJNK antibody, jnk antibody, T10F20.15 antibody, jnk1 antibody, sapk1 antibody, mapk8 antibody, zgc:112379 antibody, JNKb antibody, mapk8b antibody, mitogen-activated protein kinase 8 antibody, Stress-activated protein kinase jnk-1 antibody, basket antibody, Protein kinase superfamily protein antibody, mitogen-activated protein kinase 8 L homeolog antibody, mitogen-activated protein kinase 8b antibody, mitogen-activated protein kinase 8B-like antibody, MAPK8 antibody, jnk-1 antibody, Mapk8 antibody, bsk antibody, ATMPK8 antibody, mapk8.L antibody, mapk8b antibody, LOC109094263 antibody
Background
The JNK pathway is activated by largely distinct stimuli including inflammatory cytokines (such as TNF-alpha and IL-1), UV light, inhibitors of protein synthesis and osmotic stress. Activated MEKK1 phosphorylates SEK1 (also known as MKK4), which in turn activates SAPK (also known as JNK). JNK binds tightly to the N-terminal region of c-Jun and ATF-2, and phosphorylates c-Jun at Ser63 and Ser73 and ATF-2 at Thr69 and Thr71.Synonyms: JNK-1, JNK-46, Mitogen-activated protein kinase 8, PRKM8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1
Gene ID
5599
NCBI Accession
NP_002741
UniProt
P45983
Pathways
MAPK Signaling , WNT Signaling , TLR Signaling , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Hepatitis C , Toll-Like Receptors Cascades , Signaling of Hepatocyte Growth Factor Receptor , S100 Proteins
Recently viewed
(hide)