ING3 antibody (Isoform 1)
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- Target See all ING3 Antibodies
- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
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Binding Specificity
- AA 294-304, Isoform 1
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Reactivity
- Human
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This ING3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Characteristics
- Concentration Definition: by UV absorbance at 280 nm
- Immunogen
- This affinity purified antibody was prepared from whole Goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 294-304 of Human ING3 protein (Inhibitor of growth family, member 3). This sequence only shows homology to for ING3.
- Isotype
- IgG
- Top Product
- Discover our top product ING3 Primary Antibody
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- Application Notes
- This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Specific conditions for western blotting reactivity should be optimized by the end user. Expect a band at approximately 47 kDa in size corresponding to ING3 isoform 1 by western blotting in the appropriate cell lysate or extract.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.10 mg/mL
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
- Alternative Name
- p47 ING3 (ING3 Products)
- Synonyms
- ING3 antibody, Eaf4 antibody, ING2 antibody, MEAF4 antibody, p47ING3 antibody, 1300013A07Rik antibody, P47ING3 antibody, zgc:56327 antibody, inhibitor of growth family member 3 antibody, inhibitor of growth family, member 3 antibody, inhibitor of growth protein 3 antibody, inhibitor of growth family member 3 L homeolog antibody, ING3 antibody, Ing3 antibody, CpipJ_CPIJ009396 antibody, ing3 antibody, ing3.L antibody
- Background
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P47 ING3 is a tumor suppressor protein similar to ING1 that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Over-expression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Multiple alternatively spliced transcript variants have been observed. The accession number listed below is for variant (1) that encodes the longest isoform.
Synonyms: Inhibitor of growth family member 3 antibody, Inhibitor of growth protein 3 antibody - Gene ID
- 54556, 38201655
- UniProt
- Q9NXR8
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