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FANCA antibody (AA 995-1009)

FANCA Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN129606
  • Target See all FANCA Antibodies
    FANCA (Fanconi Anemia Group A Protein (FANCA))
    Binding Specificity
    • 15
    • 12
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 995-1009
    Reactivity
    • 58
    • 18
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 70
    • 3
    Rabbit
    Clonality
    • 71
    • 2
    Polyclonal
    Conjugate
    • 31
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FANCA antibody is un-conjugated
    Application
    • 35
    • 28
    • 13
    • 13
    • 9
    • 9
    • 9
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Cross-Reactivity
    Chimpanzee
    Characteristics
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 995-1009 of human FANCA protein.
    Isotype
    IgG
  • Application Notes
    This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a main band at approximately 163 kDa in size corresponding to FANCA by western blotting in the appropriate cell lysate or extract or human tissue.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2.2 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Smogorzewska, Matsuoka, Vinciguerra, McDonald, Hurov, Luo, Ballif, Gygi, Hofmann, DAndrea, Elledge: "Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair." in: Cell, Vol. 129, Issue 2, pp. 289-301, (2007) (PubMed).

  • Target
    FANCA (Fanconi Anemia Group A Protein (FANCA))
    Alternative Name
    FANCA (FANCA Products)
    Synonyms
    FA antibody, FA-H antibody, FA1 antibody, FAA antibody, FACA antibody, FAH antibody, FANCH antibody, AW208693 antibody, Fanconi anemia complementation group A antibody, Fanconi anemia, complementation group A antibody, FANCA antibody, Fanca antibody
    Background
    FANCA (also called Protein FACA or Fanconi anemia group A protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCA may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia
    Synonyms: FA 1 antibody, FA antibody, FA H antibody, FA1 antibody, FAA antibody, FACA antibody, FAH antibody, FANCH antibody
    Gene ID
    2175, 66880553
    UniProt
    O15360
    Pathways
    DNA Damage Repair
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