FANCE antibody (AA 1-13)

Catalog No. ABIN129609

Product Details anti-FANCE Antibody

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Binding Specificity: AA 1-13

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCE antibody is un-conjugated

Application: ELISA

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1-13 of Human FANCE. This Fanconi anemia protein promotes the nuclear accumulation of FANCC. FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage. LocusLink ID 2178, SwissProt accession number Q9HB96

Isotype: IgG

Application Details

Application Notes: This affinity purified antibody has been tested for use in ELISA against the immunizing peptide.  Reactivity in other immunoassays is unknown.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for FANCE

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Alternative Name: FANCE (FANCE Products)

Synonyms: FANCE antibody, fae antibody, face antibody, FACE antibody, FAE antibody, 2810451D06Rik antibody, AI415634 antibody, AW209126 antibody, RGD1561045 antibody, Fanconi anemia complementation group E antibody, Fanconi anemia, complementation group E antibody, FANCE antibody, fance antibody, Fance antibody

Background: Synonyms: 2810451D06Rik antibody, AI415634 antibody, AW209126 antibody, FACE antibody, FAE antibody, Fanconi anemia complementation group E antibody

Gene ID: 2178

NCBI Accession: NP_068741

UniProt: Q9HB96

Pathways: DNA Damage Repair