RIF1 antibody (AA 2406-2419)

Catalog No. ABIN129646

Product Details anti-RIF1 Antibody

Target: RIF1 (RAP1 Interacting Factor Homolog (RIF1))

Binding Specificity: AA 2406-2419

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding amino acids 2406-2419 of Mouse Rif1.

Isotype: IgG

Application Details

Application Notes: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 265 kDa in size corresponding to Rif1 by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.6 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-RIF1 antibody (ABIN129646)

Tanaka, Muto, Shima, Katoh, Sax, Tajima, Brydun, Ikura, Yoshizawa, Masai, Hoshikawa, Noda, Nio, Ochiai, Igarashi: "Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3." in: The Journal of biological chemistry, Vol. 291, Issue 12, pp. 6316-30, (2016) (PubMed).

Target Details for RIF1

Target: RIF1 (RAP1 Interacting Factor Homolog (RIF1))

Alternative Name: Rif1 (RIF1 Products)

Synonyms: 5730435J01Rik antibody, 6530403D07Rik antibody, AU016181 antibody, AW549474 antibody, D2Ertd145e antibody, RGD1562474 antibody, fc38c03 antibody, wu:fc38c03 antibody, si:dkey-89p3.2 antibody, replication timing regulatory factor 1 antibody, RAP1 interacting factor homolog (yeast) antibody, RIF1 antibody, Rif1 antibody, rif1 antibody

Background: Rif1 (also known as telomere-associated protein RIF1 and Rap1-interacting factor 1) is a mouse ortholog of the yeast Rif1 family of telomere-associated proteins identified on the basis of its high expression in primordial germ cells and embryo-derived pluripotent stem cell lines.  Mouse Rif1 is a protein involved in negative regulation of telomere length.  It is also localized to ATM dependent DNA damage foci and may act at the chromatin level to allow access to some factors.
Synonyms: DKFZp781N1478 antibody, FLJ10599 antibody, FLJ11269 antibody, FLJ12870 antibody, Rap1 interacting factor 1 antibody, Rap1 interacting factor 1 homolog antibody, RAP1 interacting factor homolog antibody

Gene ID: 51869, 68565756

UniProt: Q6PR54

Pathways: Stem Cell Maintenance