Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CD84 antibody (FITC)

CD84 Reactivity: Human FACS Host: Mouse Monoclonal CD84-1-21 FITC
Catalog No. ABIN1302945
  • Target See all CD84 Antibodies
    CD84
    Reactivity
    • 63
    • 23
    • 16
    • 1
    Human
    Host
    • 50
    • 29
    • 1
    Mouse
    Clonality
    • 50
    • 29
    • 1
    Monoclonal
    Conjugate
    • 32
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD84 antibody is conjugated to FITC
    Application
    • 47
    • 42
    • 25
    • 10
    • 9
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    Flow Cytometry (FACS)
    Specificity
    The mouse monoclonal antibody CD84.1.21 recognizes an extracellular epitope of CD84, a single chain cell surface glycoprotein of 64-82 kDa, predominantly expressed B cells, monocytes, platelets and some T cells.
    Cross-Reactivity (Details)
    Human
    Purification
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    CD84-transfected 300.19 cell line
    Clone
    CD84-1-21
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CD84 Primary Antibody
  • Application Notes
    Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
    Comment

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Reconstitution
    No reconstitution is necessary.
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Avoid prolonged exposure to light.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Romero, Zapater, Calvo, Kalko, de la Fuente, Tovar, Ockeloen, Pizcueta, Engel: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).

    Morra, Lu, Poy, Martin, Sayos, Calpe, Gullo, Howie, Rietdijk, Thompson, Coyle, Denny, Yaffe, Engel, Eck, Terhorst: "Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells." in: The EMBO journal, Vol. 20, Issue 21, pp. 5840-52, (2001) (PubMed).

    Martin, Romero, de la Fuente, Tovar, Zapater, Esplugues, Pizcueta, Bosch, Engel: "CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: adhesion is mediated by Ig-like domain 1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 7, pp. 3668-76, (2001) (PubMed).

    Sayós, Martín, Chen, Simarro, Howie, Morra, Engel, Terhorst: "Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP." in: Blood, Vol. 97, Issue 12, pp. 3867-74, (2001) (PubMed).

  • Target
    CD84
    Alternative Name
    CD84 (CD84 Products)
    Synonyms
    RGD1564553 antibody, A130013D22Rik antibody, CDw84 antibody, SLAMF5 antibody, LY9B antibody, hCD84 antibody, mCD84 antibody, CD84 molecule antibody, CD84 antigen antibody, Cd84 antibody, CD84 antibody
    Background
    CD84 Molecule,CD84 is a highly glycosylated homophilic receptor of SLAM family. It is expressed on platelets and various types of leukocytes, especially following their activation. Ligation of CD84 leads to its phosphorylation on tyrosine residues within the cytoplasmic tail. These docking sites are recognized by downstream signaling molecules, such as phosphatase SHP-2 and adaptor protein SAP/SH2D1A. The function of CD84 has not been fully elucidated yet. Although predominantly activating receptor, its modulating activity was also demonstrated.,LY9B, SLAMF5
    Gene ID
    8832
    UniProt
    Q9UIB8
You are here:
Support