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CD11b antibody (FITC)

ITGAM Reactivity: Rat FACS Host: Mouse Monoclonal OX-42 FITC
Catalog No. ABIN133349
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivity
    • 259
    • 168
    • 61
    • 33
    • 17
    • 17
    • 16
    • 14
    • 11
    • 7
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    • 5
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    • 2
    • 2
    • 1
    Rat
    Host
    • 136
    • 105
    • 103
    • 4
    • 1
    • 1
    Mouse
    Clonality
    • 250
    • 96
    • 1
    Monoclonal
    Conjugate
    • 120
    • 36
    • 29
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    • 10
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    • 3
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    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This CD11b antibody is conjugated to FITC
    Application
    • 259
    • 84
    • 76
    • 72
    • 59
    • 40
    • 36
    • 27
    • 22
    • 20
    • 13
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    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    Rat CD11b/c (macrophages)
    Purification
    Purified from ascites via Protein G Chromatography
    Immunogen
    Rat Peritoneal Macrophages . Fusion Partner: NSO/U mouse myeloma cell line . Donor: BALB/c spleen
    Clone
    OX-42
    Isotype
    IgG2a
    Top Product
    Discover our top product ITGAM Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    0.1 mg/ml
    Buffer
    FITC conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    CD11b/c (ITGAM Products)
    Synonyms
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    Background
    Anti-rat CD11b/c monoclonal antibody recognizes most macrophages including resident peritoneal macrophages, kupffer cells, but only approximately 35% of alveolar macrophages (2). ABIN133349also labels dendritic cells extensively, granulocytes and cells with morphology of microglia in the brain. It precipitates three polypeptides of MW 160, 103 and 95 kDa. ABIN133349inhibits complement mediated rosettes and is probably the rat equivalent of the human receptor for C3b called CR3. anti-rat CD11b/c monoclonal antibody should prove useful in the recognition of macrophages and microglia.
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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