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CD5 antibody (SPRD)

CD5 Reactivity: Mouse FACS Host: Rat Monoclonal B19-1 SPRD
Catalog No. ABIN135111
  • Target See all CD5 Antibodies
    CD5
    Reactivity
    • 222
    • 89
    • 58
    • 27
    • 22
    • 16
    • 15
    • 15
    • 13
    • 12
    • 11
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 167
    • 81
    • 55
    • 1
    Rat
    Clonality
    • 232
    • 70
    Monoclonal
    Conjugate
    • 110
    • 38
    • 32
    • 28
    • 13
    • 8
    • 6
    • 5
    • 4
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    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD5 antibody is conjugated to SPRD
    Application
    • 235
    • 109
    • 68
    • 67
    • 65
    • 53
    • 30
    • 29
    • 22
    • 18
    • 13
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    • 6
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    • 2
    • 2
    • 1
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    Flow Cytometry (FACS)
    Brand
    Spectral Red ™
    Specificity
    Mouse CD5, Mr 67 kDa
    Characteristics
    Rat Anti-Mouse CD5-SPRD
    Immunogen
    Unknown
    Clone
    B19-1
    Isotype
    IgG2a
    Top Product
    Discover our top product CD5 Primary Antibody
  • Application Notes
    • Applications: FC - Quality tested , IP - Reported in literature , WB - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Sample Volume
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C
  • Target
    CD5
    Alternative Name
    CD5 (CD5 Products)
    Synonyms
    CD5 antibody, Ly-1 antibody, Ly-12 antibody, Ly-A antibody, Lyt-1 antibody, LEU1 antibody, T1 antibody, CD5 molecule antibody, CD5 antigen antibody, CD5 molecule like antibody, Cd5 molecule antibody, CD5 antibody, Cd5 antibody, CD5L antibody
    Background
    CD5/Lyt-1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors.
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