ICAM1 antibody
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- Target See all ICAM1 Antibodies
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This ICAM1 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- Mouse/Porcine CD54, Mr 95 kDa
- Characteristics
- Rat Anti-Mouse CD54-UNLB
- Purification
- Purified
- Immunogen
- Mouse NS-1 cells
- Clone
- YN1-1-7-4
- Isotype
- IgG2b
- Top Product
- Discover our top product ICAM1 Primary Antibody
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- Application Notes
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , WB - Reported in literature , IP - Reported in literature , Block - Reported in literature , Purification - Reported in literature
- Working Dilutions: Flow Cytometry FITC, BIOT, AF488, and PACBLU conjugates 1 g/106 cells PE, APC, AF647, and AF700 conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Comment
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In vitro blocking studies
- Sample Volume
- 1 mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
- Preservative
- Without preservative
- Handling Advice
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C
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Coxsackievirus and adenovirus receptor mediates the responses of endothelial cells to fluid shear stress." in: Experimental & molecular medicine, Vol. 51, Issue 11, pp. 1-15, (2020) (PubMed).
: "
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Coxsackievirus and adenovirus receptor mediates the responses of endothelial cells to fluid shear stress." in: Experimental & molecular medicine, Vol. 51, Issue 11, pp. 1-15, (2020) (PubMed).
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- Target
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- Alternative Name
- CD54 (ICAM1 Products)
- Synonyms
- BB2 antibody, CD54 antibody, P3.58 antibody, Icam-1 antibody, Ly-47 antibody, MALA-2 antibody, ICAM antibody, ICAM-1 antibody, ICAM1 antibody, intercellular adhesion molecule 1 antibody, intercellular adhesion molecule-1 antibody, ICAM1 antibody, Icam1 antibody, ICAM-1 antibody
- Target Type
- Viral Protein
- Background
- CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN-γ, IL-1, TNF-α, lipopolysaccharide and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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