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L-Selectin antibody

SELL Reactivity: Mouse FACS Host: Rat Monoclonal MEL-14 unconjugated
Catalog No. ABIN135253
  • Target See all L-Selectin (SELL) Antibodies
    L-Selectin (SELL) (Selectin L (SELL))
    Reactivity
    • 99
    • 74
    • 31
    • 12
    • 9
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Mouse
    Host
    • 79
    • 55
    • 49
    Rat
    Clonality
    • 130
    • 48
    • 3
    Monoclonal
    Conjugate
    • 66
    • 26
    • 21
    • 14
    • 13
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This L-Selectin antibody is un-conjugated
    Application
    • 135
    • 49
    • 48
    • 47
    • 35
    • 28
    • 16
    • 11
    • 11
    • 9
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    Mouse CD62L, Mr 74 kDa on lymphocytes and Mr 95 kDa on neutrophils
    Characteristics
    Rat Anti-Mouse CD62L-LE/AF
    Purification
    boric acid precipitation
    Endotoxin Level
    Low endotoxin
    Immunogen
    C3H/eb cloned mouse B cell lymphoma 38C-13
    Clone
    MEL-14
    Isotype
    IgG2a
    Top Product
    Discover our top product SELL Primary Antibody
  • Application Notes
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature , Cyto - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PACBLU conjugate 0.3 g/106 cells PE, APC, SPRD, PE/CY7, APC/CY7, AF488, AF647, and AF700 0.1 g/106 cells conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Comment

    In vivo and in vitro blocking of adhesion, Cytotoxicity studies

    Sample Volume
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    Preservative
    Azide free
    Handling Advice
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    -20 °C
    Storage Comment
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • Target
    L-Selectin (SELL) (Selectin L (SELL))
    Alternative Name
    CD62L (SELL Products)
    Synonyms
    CD62L antibody, LAM1 antibody, LECAM1 antibody, LEU8 antibody, LNHR antibody, LSEL antibody, LYAM1 antibody, PLNHR antibody, TQ1 antibody, A.11 antibody, L-selectin antibody, LECAM-1 antibody, SELE antibody, AI528707 antibody, Lnhr antibody, Ly-22 antibody, Ly-m22 antibody, Lyam-1 antibody, Lyam1 antibody, selectin L antibody, selectin, lymphocyte antibody, SELL antibody, Sell antibody
    Target Type
    Chemical
    Background
    CD62L, also known as L-selectin, is a type I transmembrane glycoprotein with lectin-like and Epidermal Growth Factor-like domains. It binds to sialylated oligosaccharide determinants on high endothelial venules (HEV) in peripheral lymph nodes. In the mouse, CD62L is expressed on most thymocytes and on peripheral leukocytes, including B and T lymphocytes, neutrophils, monocytes and eosinophils. This member of the selectin family of cell adhesion molecules appears to be required for lymphocyte homing to peripheral lymph nodes and for leukocyte extravasation at sites of inflammation. Expression of CD62L on lymphocytes and neutrophils is rapidly down-regulated upon cell activation and the level of CD62L expression, along with other markers, distinguishes naive T cells from effector/memory T cells.
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