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Transferrin Receptor antibody

TFRC Reactivity: Mouse FACS Host: Rat Monoclonal RI7217 unconjugated
Catalog No. ABIN135263
  • Target See all Transferrin Receptor (TFRC) Antibodies
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Reactivity
    • 187
    • 76
    • 27
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 108
    • 101
    • 26
    • 1
    • 1
    Rat
    Clonality
    • 141
    • 94
    • 1
    Monoclonal
    Conjugate
    • 106
    • 25
    • 19
    • 14
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Transferrin Receptor antibody is un-conjugated
    Application
    • 140
    • 137
    • 69
    • 68
    • 50
    • 39
    • 23
    • 20
    • 18
    • 12
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    Mouse CD71, Mr 95 kDa
    Characteristics
    Rat Anti-Mouse CD71-LE/AF
    Purification
    Protein A
    Endotoxin Level
    Low endotoxin
    Immunogen
    DMSO induced Friend erythroleukemia 745.6
    Clone
    RI7217
    Isotype
    IgG2a
    Top Product
    Discover our top product TFRC Primary Antibody
  • Application Notes
    • Applications: FC - Quality tested , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature , Sep - Reported in literature , Drug Delivery - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Sample Volume
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    Preservative
    Azide free
    Handling Advice
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    -20 °C
    Storage Comment
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • Target
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Alternative Name
    CD71 (TFRC Products)
    Synonyms
    Trfr antibody, LOC100219280 antibody, tfr antibody, cd71 antibody, tfr1 antibody, trfr antibody, CD71 antibody, T9 antibody, TFR antibody, TFR1 antibody, TR antibody, TRFR antibody, p90 antibody, 2610028K12Rik antibody, AI195355 antibody, AI426448 antibody, AU015758 antibody, E430033M20Rik antibody, Mtvr-1 antibody, Mtvr1 antibody, transferrin receptor antibody, TFRC antibody, Tfrc antibody, tfrc antibody
    Background
    CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens, presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor chain.
    Pathways
    Transition Metal Ion Homeostasis
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