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TCRgd antibody (FITC)

Reactivity: Mouse FACS Host: Hamster Monoclonal UC7-13D5 FITC
Catalog No. ABIN135303
  • Target
    TCRgd
    Reactivity
    • 4
    • 3
    Mouse
    Host
    • 4
    • 3
    Hamster
    Clonality
    • 7
    Monoclonal
    Conjugate
    • 2
    • 2
    • 2
    • 1
    FITC
    Application
    Flow Cytometry (FACS)
    Specificity
    Mouse TCR
    Characteristics
    Hamster Anti-Mouse TCRgd-FITC
    Immunogen
    Mouse T cell clone G8
    Clone
    UC7-13D5
    Isotype
    IgG
  • Application Notes
    • Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Depletion - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE and SPRD conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Comment

    In vivo depletion of gd TCR-expressing T cell

    Sample Volume
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg in 1.0 mL of PBS/Sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C
  • Target
    TCRgd
    Background
    The TCR heterodimer of the CD3/T-cell receptor complex is clonotypic and consists of Ig-like variable and constant domains.1 It is expressed during thymopoiesis and on the small subpopulation of TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are + and have limited receptor diversity. The TCR heterodimer recognizes peptide antigen bound to MHC antigens, and subsequent signal transduction mediated by the invariant chains leads to T cell activation.
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