Niban antibody (pSer602)

Catalog No. ABIN1355871

Product Details anti-Niban Antibody

Target: Niban (FAM129A) (Family with Sequence Similarity 129, Member A (FAM129A))

Binding Specificity: pSer602

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Niban antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: The antibody detects endogenous level of Niban only when phosphorylated at serine 602.

Immunogen: Peptide sequence around phosphorylation site of pSer602 (R-A-S (p) -A-I) derived from Human Niban. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Application Details

Application Notes: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

References for anti-Niban antibody (ABIN1355871)

Ji, Ding, Hawke, Xing, Jiang, Mills, Lu: "AKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosis." in: EMBO reports, Vol. 13, Issue 6, pp. 554-60, (2012) (PubMed).

Target Details for Niban

Target: Niban (FAM129A) (Family with Sequence Similarity 129, Member A (FAM129A))

Alternative Name: Niban (FAM129A Products)

Synonyms: C1orf24 antibody, NIBAN antibody, AI256368 antibody, AU019833 antibody, Niban antibody, family with sequence similarity 129 member A antibody, family with sequence similarity 129, member A antibody, FAM129A antibody, Fam129a antibody

Background: Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response Vill

Molecular Weight: 150 kDa

NCBI Accession: NP_443198

UniProt: Q9BZQ8