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CD8 alpha antibody (Biotin)

CD8A Reactivity: Chicken FACS Host: Mouse Monoclonal EP72 Biotin
Catalog No. ABIN135592
  • Target See all CD8 alpha (CD8A) Antibodies
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Reactivity
    • 192
    • 119
    • 40
    • 36
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    • 7
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    • 1
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    Chicken
    Host
    • 143
    • 129
    • 100
    • 1
    Mouse
    Clonality
    • 269
    • 100
    • 1
    Monoclonal
    Conjugate
    • 131
    • 43
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD8 alpha antibody is conjugated to Biotin
    Application
    • 287
    • 105
    • 92
    • 66
    • 54
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    Flow Cytometry (FACS)
    Specificity
    Chicken CD8α, Mr 34 kDa
    Characteristics
    Mouse Anti-Chicken CD8a-BIOT
    Purification
    Ion exchange column
    Immunogen
    Chicken splenocytes
    Clone
    EP72
    Isotype
    IgG2b
    Top Product
    Discover our top product CD8A Primary Antibody
  • Application Notes
    • Applications: FC - Quality tested , IHC-FS - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Sample Volume
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg in 1.0 mL of PBS/Sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C
  • Target
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Alternative Name
    CD8a (CD8A Products)
    Synonyms
    cd8 antibody, LOC100136450 antibody, BB154331 antibody, Ly-2 antibody, Ly-35 antibody, Ly-B antibody, Lyt-2 antibody, zgc:136643 antibody, CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, RHACD8-4 antibody, CD8a molecule antibody, uncharacterized LOC100125537 antibody, CD8 alpha antibody, CD8 antigen, alpha chain antibody, T-cell surface glycoprotein CD8 alpha chain antibody, Cd8a antibody, LOC100125537 antibody, LOC100136450 antibody, CD8A antibody, cd8a antibody, LOC100126556 antibody
    Background
    In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two chains, and (ii) a heterodimer of an chain and a chain. Chicken CD8 is expressed on approximately 80 % of thymocytes, 45 % of blood mononuclear cells and 50 % of spleen cells, but < 1 % of cells in the bursa and bone marrow. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8- and CD8-chains, a relatively large proportion of the CD8+ TCR- cells in the spleens of embryos and young chicks express only the -chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR- CD8 cells in the chicken that is not found in rodents.
    Pathways
    TCR Signaling
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