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VCAM1 antibody

VCAM1 Reactivity: Human FACS Host: Mouse Monoclonal 1-G11B1 unconjugated
Catalog No. ABIN135716
  • Target See all VCAM1 Antibodies
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Reactivity
    • 135
    • 96
    • 55
    • 25
    • 15
    • 8
    • 8
    • 4
    • 3
    • 1
    Human
    Host
    • 96
    • 71
    • 33
    • 5
    • 1
    • 1
    Mouse
    Clonality
    • 114
    • 91
    • 1
    Monoclonal
    Conjugate
    • 93
    • 27
    • 24
    • 12
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VCAM1 antibody is un-conjugated
    Application
    • 115
    • 96
    • 53
    • 42
    • 35
    • 32
    • 27
    • 26
    • 21
    • 16
    • 16
    • 13
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    Human/Porcine CD106, Mr 110 kDa
    Characteristics
    Mouse Anti-Human CD106-UNLB
    Purification
    Purified
    Immunogen
    Unknown
    Clone
    1-G11B1
    Isotype
    IgG1
    Top Product
    Discover our top product VCAM1 Primary Antibody
  • Application Notes
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB-NR - Reported in literature , ELISA - Reported in literature , Block - Reported in literature , Adhesion - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, and PE conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Sample Volume
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Preservative
    Without preservative
    Handling Advice
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C
  • Target
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Alternative Name
    CD106 (VCAM1 Products)
    Synonyms
    CD106 antibody, INCAM-100 antibody, Vcam-1 antibody, VCAM1B antibody, fi76d06 antibody, wu:fi76d06 antibody, zgc:158875 antibody, VCAM1 antibody, vascular cell adhesion molecule 1 antibody, vascular cell adhesion molecule 1b antibody, VCAM1 antibody, Vcam1 antibody, vcam1b antibody, VCAM-1 antibody
    Background
    CD106, also known as INCAM-1, is a 100-110 kDa vascular adhesion cell adhesion molecule-1 (VCAM-1) that is member of the immunoglobulin superfamily. CD106 is expressed predominantly on cytokine-activated vascular endothelium but has also been identified on interfollicular dendritic cells, some macrophages and bone marrow stromal cells. Endothelial CD106 binds the integrins 41 (CD49d/CD29, VLA-4) and 47 and contributes to extravasation of lymphocytes, monocytes, basophils and eosinophils (but not neutrophils) from blood vessels, particularly at sites of inflammation. Unlike the 2 integrins, the CD106-VLA-4 interaction can mediate both the initial tethering and rolling of lymphocytes on endothelium as well as their subsequent arrest and firm adhesion. CD106 expressed on non-vascular tissues has been implicated in the interaction of hematopoietic progenitors with bone marrow stromal cells, B cell binding to follicular dendritic cells, costimulation of T cells, and embryonic development.
    Pathways
    Carbohydrate Homeostasis
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