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CD8 antibody (CD8a Molecule) (FITC)

Details for Product anti-CD8A Antibody No. ABIN135735, Supplier: Login to see
Antigen
  • cd8
  • LOC100136450
  • BB154331
  • Ly-2
  • Ly-35
  • Ly-B
  • Lyt-2
  • zgc:136643
  • CD8
  • Leu2
  • MAL
  • p32
  • RHACD8-4
Alternatives
anti-Human CD8 antibody for Immunohistochemistry (Frozen Sections)
Reactivity
Human
797
427
145
68
28
27
25
22
20
16
15
12
12
11
11
10
10
9
8
8
3
3
2
2
2
2
1
1
1
Host
Mouse
998
418
168
Clonality (Clone)
Monoclonal ()
Conjugate
This CD8 antibody is conjugated to FITC
257
200
126
87
31
31
28
18
18
17
16
15
13
11
10
10
10
9
8
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC)
1225
295
237
213
146
118
114
100
78
37
33
25
23
18
17
10
7
7
6
6
5
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
Supplier
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Clone RFT-8
Isotype IgG1
Characteristics The antibody detects: Human CD8
Purification Ion exchange
Alternative Name CD8 (CD8A Antibody Abstract)
Background CD8 is a 32 kDa transmembrane glycoprotein expressed as either a CD8 homodimer or CD8 heterodimer. It is expressed on the cytotoxic/suppressor subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC Class I-restricted TCR's in antigen recognition.
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling
Application Notes Working Dilution:
FACS: 10 µL/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Buffer Product is supplied as 100 tests in 1.0 mL PBS / NaN3.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.
Storage 4 °C
Background publications Zamoyska: "The CD8 coreceptor revisited: one chain good, two chains better." in: Immunity, Vol. 1, Issue 4, pp. 243-6, 1995 (PubMed).