You are viewing an incomplete version of our website. Please click to reload the website as full version.

Transferrin Receptor (p90, CD71) (TFRC) antibody

Details for Product No. ABIN135804, Supplier: Log in to see
Antigen
  • TFRC
  • tfr
  • cd71
  • tfr1
  • trfr
  • LOC100219280
  • 2610028K12Rik
  • AI195355
  • AI426448
  • AU015758
  • CD71
  • E430033M20Rik
  • Mtvr-1
  • Mtvr1
  • TFR
  • TFR1
  • TR
  • Trfr
  • p90
  • T9
  • TRFR
Reactivity
Human
285
144
41
10
6
6
6
4
4
2
2
2
Host
Mouse
236
111
73
9
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
65
53
45
20
7
5
5
4
2
2
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
302
127
82
79
61
49
34
17
11
10
9
5
4
3
2
2
2
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Clone RVS10
Isotype IgG1
Characteristics The antibody detects: Human CD71
Purification Purified
Alternative Name CD71 (TFRC Antibody Abstract)
Background CD71 is a 95 kDa type II heterodimeric transmembrane glycoprotein that is the receptor for transferrin. CD71 expression is very low on resting leukocytes but is upregulated upon activation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin.
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways
Application Notes Working Dilution:
FACS: 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Sample Volume 1 mL
Restrictions For Research Use only
Buffer Product is supplied as 0.1 mg purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.
Preservative Azide free
Handling Advice Each reagent is stable for the period shown on the bottle label if stored as directed.
Storage 4 °C
Background publications Hentze, Kühn: "Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 16, pp. 8175-82, 1996 (PubMed).