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Details for Product No. ABIN135804

Transferrin Receptor (p90, CD71) (TFRC) antibody

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Antigen
Synonyms trfr, CD71, T9, TFR, TFR1, TR, TRFR, p90, TFRC, tfr, cd71, tfr1, LOC100219280
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN135804
Quantity 0.1 mg
Price
135.30 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Clone RVS10
Isotype IgG1
Characteristics The antibody detects: Human CD71
Purification Purified
Alternative Name CD71
Background CD71 is a 95 kDa type II heterodimeric transmembrane glycoprotein that is the receptor for transferrin. CD71 expression is very low on resting leukocytes but is upregulated upon activation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin.
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Working Dilution:
FACS: 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Sample Volume 1 mL
Restrictions For Research Use only
Buffer Product is supplied as 0.1 mg purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.
Preservative Azide free
Handling Advice Each reagent is stable for the period shown on the bottle label if stored as directed.
Storage 4 °C
Hentze, Kühn: "Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 16, pp. 8175-82, 1996 (PubMed).

Alternatives for antigen "Transferrin Receptor (p90, CD71) (TFRC)", type "Antibodies"
Hosts (196), (93), (42), (2), (1)
Reactivities (220), (122), (27), (12), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applications (226), (85), (75), (74), (38), (29), (19), (17), (13), (12), (4), (3), (2), (1), (1), (1), (1)
Conjugates (46), (35), (33), (9), (6), (2), (2), (1), (1), (1), (1)
Epitopes (10), (8), (5), (3), (3), (2), (2), (1), (1), (1), (1)
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