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Details for Product No. ABIN136318

Centromere Protein F (CENPF) antibody

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Antigen
Synonyms CENF, hcp-1, PRO1779, CMF1, im:7140452, im:7144238, im:7154719, im:7156761, si:ch211-152h14.2, Lek1, mitosin, AI325968, 6530404A22Rik, LOC100222985
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality Monoclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN136318
Quantity 0.1 mg
Price
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Immunogen Protein fragment expressed in E. coli corresponding to amino acids 1759-2093.
Isotype IgG2a
Purification Protein G affinity purified
Alternative Name CENP-F
Background Mitosin-14C10 recognizes mitosin, a 350kDa phosphoprotein that is specifically involved in mitotic-phase progression. Mitosin is expressed throughout S, G2, and M phases of the cell cycle but is absent in G0 and G1. It associates with the mitotic apparatus during M-phase, and is redistributed from the nucleus to the centromere, spindle, and midbody during M-phase progression. Its usefulness as a proliferation marker is under active investigation.
Application Notes Western (1:500)
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer Phosphate-buffered saline, pH 7.2, no preservative added.
Storage -80 °C
Zhu, Mancini, Chang et al.: "Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression." in: Molecular and cellular biology, Vol. 15, Issue 9, pp. 5017-29, 1995 (PubMed).

Clark, Allred, Hilsenbeck et al.: "Mitosin (a new proliferation marker) correlates with clinical outcome in node-negative breast cancer." in: Cancer research, Vol. 57, Issue 24, pp. 5505-8, 1998 (PubMed).

Alternatives for antigen "Centromere Protein F (CENPF)", type "Antibodies"
Hosts (29), (11), (7)
Reactivities (44), (1), (1), (1), (1), (1)
Applications (26), (18), (15), (10), (9), (8), (6), (2), (1), (1)
Conjugates (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (4)
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