You are viewing an incomplete version of our website. Please click to reload the website as full version.

ATM antibody (Ataxia Telangiectasia Mutated)

Details for Product anti-ATM Antibody No. ABIN136325, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

(297), (74), (30), (6), (4), (1), (1)
(213), (58), (16), (8), (4)
This ATM antibody is un-conjugated
(8), (8), (6), (6), (6), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Immunoprecipitation (IP), Western Blotting (WB)
(171), (79), (71), (52), (42), (41), (25), (22), (16), (11), (5), (4), (4), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 0.1 mg
Shipping to United States ( )
Immunogen Recombinant protein expressed in E. coli corresponding to amino acids 980-1512.
Isotype IgG1
Cross-Reactivity Monkey, Mouse (Murine), Rat (Rattus)
Purification Protein G affinity purified
Alternative Name ATM (ATM Antibody Abstract)
Background ATM-3E8 recognizes full-length ATM, a 370kDa nuclear phosphoprotein, which is involved in the autosomal recessive disease ataxia telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation and response to DNA repair. The C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases). Its usefulness to monitor altered ATM expression in cancer is under active investigation.
Research Area Cancer, DNA/RNA
Pathways p53 Signaling, Apoptosis, DNA Damage Repair
Application Notes For IP: Use at a concentration of 2-10 ug/ml. For WB: Use at a concentration of 1-2 ug/ml. Predicted moolecular weight: 350kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer Phosphate-buffered saline, pH7.4, containing no preservatives
Supplier Images
Western Blotting (WB) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (ABIN136325) anti-Ataxia Telangiectasia Mutated (ATM) antibody
Background publications Chen, Lin, Lieberman et al.: "ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation." in: The Journal of biological chemistry, Vol. 276, Issue 19, pp. 16580-6, 2001 (PubMed).

Stein: "The effect of adrenaline and of alpha- and beta-adrenergic blocking agents on ATP concentration and on incorporation of 32Pi into ATP in rat fat cells." in: Biochemical pharmacology, Vol. 24, Issue 18, pp. 1659-62, 1976 (PubMed).

Catalog No. ABIN136325
Contact our Customer Service for availability and price in your country.

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)