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Ataxia Telangiectasia and Rad3 Related (ATR) antibody

Details for Product No. ABIN136334
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Antigen
Synonyms
FCTCS, FRP1, MEC1, SCKL, SCKL1, XATR, frp1, mec1, sckl, sckl1, ARABIDOPSIS THALIANA ATAXIA TELANGIECTASIA-MUTATED AND RAD3-RELATED, ATATR, ATRAD3, Ataxia telangiectasia-mutated and RAD3-related, MHK7. ... show more
FCTCS, FRP1, MEC1, SCKL, SCKL1, XATR, frp1, mec1, sckl, sckl1, ARABIDOPSIS THALIANA ATAXIA TELANGIECTASIA-MUTATED AND RAD3-RELATED, ATATR, ATRAD3, Ataxia telangiectasia-mutated and RAD3-related, MHK7.5, MHK7_5, ATR, si:dkey-231j24.1 show less
Reactivity
Human
(20), (8), (4), (2), (2), (1), (1), (1), (1)
Host
Mouse
(18), (5)
Clonality
Monoclonal
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(16), (7), (6), (2), (1)
Pubmed 3 references available
Quantity 0.1 mg
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Catalog No. ABIN136334
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Immunogen Recombinant fragment, corresponding to amino acids 710-1100 of Human ATR.
Isotype IgG
Purification Protein G affinity purified
Alternative Name ATR / FRP1
Background Ataxia Telangiectasia Mutated (ATM) and Rad3-related (ATR) protein is a member of the phosphatidyl-inositol 3-kinase (PI 3-kinase) like family of protein kinases. ATR has a predicted molecular mass of approximately 301 kDa, and it has been shown to be involved in cellular responses to DNA damage. Specifically, it plays a role in checkpoint activation in response to either the presence of stalled replication forks, or by the presence of lesions caused by UV light. Inactivation of ATR is an embryonic lethal event in mice.
Application Notes For WB: Use at a dilution of 1:500-1,000. For IP and IF information please refer to publications. Not yet tested in other applications. Optimal dilution should be determind by the researcher.
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer Phosphate-buffered saline, pH7.2
Supplier Images
anti-Ataxia Telangiectasia and Rad3 Related (ATR) antibody anti-Ataxia Telangiectasia and Rad3 Related (ATR) antibody
General Abraham: "Cell cycle checkpoint signaling through the ATM and ATR kinases." in: Genes & development, Vol. 15, Issue 17, pp. 2177-96, 2001 (PubMed).

Bradbury, Jackson: "ATM and ATR." in: Current biology : CB, Vol. 13, Issue 12, pp. R468, 2003 (PubMed).

Wu, Shell, Liu et al.: "ATR-dependent checkpoint modulates XPA nuclear import in response to UV irradiation." in: Oncogene, Vol. 26, Issue 5, pp. 757-64, 2007 (PubMed).

Hosts (18), (5)
Reactivities (20), (8), (4), (2), (2), (1), (1), (1), (1)
Applications (16), (7), (6), (2), (1)
Epitopes (3), (2), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN136334
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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