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Details for Product No. ABIN137665

Heme Oxygenase (Decycling) 1 (HMOX1) antibody

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Antigen
Synonyms
HO1, HO-1, Hmox, Hemox, Hsp32, D8Wsu38e, Ho1, Heox, Ho-1, HEOXG, hsp32, Hmox1, HMOX1D, HSP32, bK286B10, HMOX1, MGC132176, wu:fc27c04, zgc:65984, ARABIDOPSIS THALIANA HEME OXYGENASE 1, ATHO1, F18A8.4,  ... show more
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality Monoclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Flow Cytometry (FACS), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN137665
Quantity 50 µg
Price
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Immunogen Synthetic peptide: MERPQPDSMPQDLSEALKEATKEVHTQAEN, corresponding to amino acids 1-30 of Human Heme Oxygenase 1.
Isotype IgG1
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Protein G affinity purified
Alternative Name Heme oxygenase 1 / HMOX1
Background Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules, biliverdin and carbon monoxide. HO consists of two homologous isozymes, an inducible HO1 and a constitutively expressed HO2. HO1 is induced by a wide variety of stimuli including conditions of oxidative stress, inflammatory agents, transforming growth factor beta and heat shock. The increase in expression of HO1 is thought to be a cellular defense mechanism against oxidative stress since elevated HO could eventually generate more bilirubin, an anti-oxidant.
Application Notes Use at a concentration of 10
Restrictions For Research Use only
Format Liquid
Concentration Batch dependent within range: 0.80-1.00 mg/ml
Buffer 50% Glycerol, PBS, 0.1mM PMSF.
Preservative Sodium azide
Storage -20 °C
Yoshida, Biro, Cohen et al.: "Human heme oxygenase cDNA and induction of its mRNA by hemin." in: European journal of biochemistry / FEBS, Vol. 171, Issue 3, pp. 457-61, 1988 (PubMed).

Foresti, Sarathchandra, Clark et al.: "Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: a link to apoptosis." in: The Biochemical journal, Vol. 339 ( Pt 3), pp. 729-36, 1999 (PubMed).

Elbirt, Bonkovsky: "Heme oxygenase: recent advances in understanding its regulation and role." in: Proceedings of the Association of American Physicians, Vol. 111, Issue 5, pp. 438-47, 1999 (PubMed).

Alternatives for antigen "Heme Oxygenase (Decycling) 1 (HMOX1)", type "Antibodies"
Hosts (78), (36), (1)
Reactivities (85), (56), (40), (24), (21), (19), (14), (12), (5), (5), (4), (2), (2), (1)
Applications (98), (46), (30), (27), (20), (19), (11), (10), (10), (8), (4), (3), (2), (2), (1), (1), (1)
Conjugates (8), (6), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (13), (10), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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