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Details for Product No. ABIN138057

Cell Division Cycle 34 Homolog (S. Cerevisiae) (CDC34) antibody

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Synonyms E2-CDC34, UBC3, UBCH3, UBE2R1, e2-cdc34, ubc3, ube2r1, CDC34, DNA6, CDC34B, UBE2R2
»Alternatives Human
»Alternatives Mouse
Clonality Monoclonal
»Alternatives Un-conjugated
»Alternatives Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN138057
Quantity 0.1 mg
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Immunogen Full-length human Cdc34 expressed in E. coli.
Isotype IgG1
Purification Protein G affinity purified
Alternative Name CDC34
Background Cdc34 is a ubiquitin conjugating enzyme (UBC) or E2 that has been shown to be essential for the G1 to S phase transition in S. cerevisiae. Human Cdc34 fully complements the budding yeast Cdc34 temperature sensitive mutant phenotype. In egg extracts of the frog Xenopus laevis, Cdc34 has been shown to be required for the onset of DNA replication and appears to function in a multi-protein complex. Also, Cdc34 is highly conserved among vertebrates and is likely to function in a similar manner in all eukaryotes to regulate the start of DNA synthesis.
Research Area Cell Cycle, CD Antigens, Surface Receptors of Immune Cells
Application Notes Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer Phosphate-buffered saline, pH 7.2, no preservative added.
Storage -80 °C
Goebl, Yochem, Jentsch et al.: "The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme." in: Science (New York, N.Y.), Vol. 241, Issue 4871, pp. 1331-5, 1988 (PubMed).

Tyers, Willems: "One ring to rule a superfamily of E3 ubiquitin ligases." in: Science (New York, N.Y.), Vol. 284, Issue 5414, pp. 601, 603-4, 1999 (PubMed).

Koepp, Harper, Elledge: "How the cyclin became a cyclin: regulated proteolysis in the cell cycle." in: Cell, Vol. 97, Issue 4, pp. 431-4, 1999 (PubMed).

Alternatives for antigen "Cell Division Cycle 34 Homolog (S. Cerevisiae) (CDC34)", type "Antibodies"
Hosts (29), (13)
Reactivities (42), (21), (21), (12), (12), (12), (12), (12)
Applications (32), (12), (12), (10), (7), (3), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (2), (2), (1), (1), (1)