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LGR4 antibody

LGR4 Reactivity: Human, Mouse FACS, cELISA Host: Rat Monoclonal BBX-3A8 unconjugated
Catalog No. ABIN1381741
  • Target See all LGR4 Antibodies
    LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))
    Reactivity
    • 34
    • 12
    • 11
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 27
    • 4
    • 3
    Rat
    Clonality
    • 27
    • 7
    Monoclonal
    Conjugate
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGR4 antibody is un-conjugated
    Application
    • 12
    • 10
    • 8
    • 7
    • 4
    • 4
    • 2
    • 1
    Flow Cytometry (FACS), Cell-ELISA (cELISA)
    Specificity
    Anti-human LGR4
    Cross-Reactivity
    Mouse (Murine)
    Characteristics
    Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    Purification
    Protein G
    Immunogen
    genetic immunisation with cDNA encoding human LGR4
    Clone
    BBX-3A8
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product LGR4 Primary Antibody
  • Application Notes
    Flow cytometry: 1.2 µg/10^6 cells
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    Comment

    Synonyms: GPR48

    Restrictions
    For Research Use only
  • Buffer
    PBS, pH 7.2
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C
    Storage Comment
    short term: 2 °C - 8 °C, long term: -20 °C
  • Target
    LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))
    Alternative Name
    LGR4 (LGR4 Products)
    Synonyms
    BNMD17 antibody, GPR48 antibody, 9130225G07 antibody, A330106J01Rik antibody, A930009A08Rik antibody, Gpr48 antibody, leucine rich repeat containing G protein-coupled receptor 4 antibody, leucine-rich repeat-containing G protein-coupled receptor 4 antibody, LGR4 antibody, Lgr4 antibody
    Background
    LGR4 (Leucine-rich repeat- containing G protein-coupled receptor 4, GPR48) belongs to the superfamily of G protein-coupled receptors (GPCRs). It is a 951 amino acid multi-pass membrane protein and has multiple N-terminal leucine-rich repeats, which are important for interaction with the glycoprotein ligands, and 7 transmembrane domains. LGR4 is highly expressed in the adult human pancreas but also with moderate levels of expression in placenta, kidney, brain and heart. LGR4 functions as an orphan receptor that may be involved in physiologic activities throughout the cell. It is overexpressed in various cancer types and is thought to enhance carcinoma invasiveness and metastasis, suggesting an important role in tumor progression.
    UniProt
    Q9BXB1
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