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Fibrinogen (Fbg) antibody

Antigen

Fibrinogen (Fbg)
Synonyms fib2, MGC53620, fibrinogen, Fib, ENSMUSG00000059807, Fba5e, Ac1873, MGC156536, sb:cb892, zgc:92117, wu:fa55c12, wu:fi39d04, FGA, MGC128011
Clonality Polyclonal
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Application
Alternatives Enzyme Immunoassay (EIA), Western Blotting (WB)
Catalog no. ABIN138237
Quantity 0.1 mg  (Batch Dependent)  (Variants)
Price Product not available in this region.
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Additional Information
Application Details Alternatives Secondary Antibodies Variants back to top

Alternative name Fibrinogen
Immunogen Fibrin degradation products
Isotype IgG1  (Matching secondary antibodies)
Description Fibrinogen is the main protein of blood coagulation system. It is a large protein (MW 340 kDa) and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1-16 amino acids) and B (1-17 amino acids) are released by thrombin from the N-terminal parts of alpha- and beta-chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases.
Specificity Fibrinogen, Fibrin degradation products

Application Details
Alternatives Secondary Antibodies Variants back to top

Application Notes ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Can be paired for ELISA with ABIN138234 Mouse monoclonal [27C8] to Fibrinogen as detection and ABIN137192 Mouse monoclonal [40F11] to Fibrinogen as capture. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Concentration Batch Dependent
Purity Protein A purified
Buffer Phosphate-buffered saline, pH7.4, containing 0.1% sodium azide
Storage Keep as concentrated solution, aliquot and store at 4C. Do not freeze.
Research Area Cardiovascular, Atherosclerosis, Extracellular Matrix, Coagulation
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies Variants back to top

Alternatives for antigen "Fibrinogen (Fbg)", type "Antibodies"
Hosts Rabbit (129), Goat (90), Mouse (80), Sheep (40), Chicken (6), Rat (2)
Reactivities Human (221), Mouse (Murine) (34), Rat (Rattus) (24), Rabbit (20), Dog (Canine) (14), Pig (Porcine) (9), Cow (Bovine) (4)
Applications Western Blotting (WB) (150), ELISA (130), Immunofluorescence (IF) (121), Flow Cytometry (FACS) (90), Enzyme Immunoassay (EIA) (65), Immunoprecipitation (IP) (46), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (32), Immunodiffusion (ID) (31), Radioimmunoassay (RIA) (31), ELISA (Detection) (20), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (19), Immunohistochemistry (Frozen Sections) (IHC (fro)) (19), Immunohistochemistry (IHC) (16), Immunoelectrophoresis (IEP) (13), Immunocytochemistry (ICC) (11), Radial Immunodiffusion (RID) (9), To be determined by user (TBD) (7), Dot Blot (Dot) (6), Immunoelectron Microscopy (IEM) (6), ELISA (Capture) (5), Magnetic Beads (MB) (4), Affinity Chromatography (AC) (1), Blocking Antibody (Inhibition) (1), Gel Shift (GS) (1), Immunoturbidimetry (IT) (1), Nephelometry (Neph) (1), Ouchterlony Double Diffusion (ODD) (1)
Conjugates Biotin (36), HRP (30), FITC (27), Gold (7), Cy3 (6), Cy5 (6), Cy5.5 (6), PE (6), PE,Cy3 (6), PE,Cy5 (6), Alexa Flour 488 (5), Cy7 (5), PE,Cy7 (5), RBITC (5), Alexa Fluor 488 (4), Alexa Fluor 350 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), PE,Cy5.5 (3)
Epitopes Insoluble Fraction Oxidized (2), Oxidized Soluble Fraction (2), Total Fraction Oxidised (2)