TNFRSF10A antibody

Catalog No. ABIN1383733

Product Details anti-TNFRSF10A Antibody

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF10A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Specificity: Recognises a 43-46 kDa protein

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: Recombinant human TRAIL R1/Fc chimera,Myeloma X63/AG.8653 x Balb/c spleen cells

Clone: B-N28

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months

References for anti-TNFRSF10A antibody (ABIN1383733)

Lin, Chen, Yue, Zou, Benbrook, Liu, Le, Berlin, Khuri, Sun: "CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells." in: Cancer research, Vol. 68, Issue 13, pp. 5335-44, (2008) (PubMed).

Raja, Chen, Yue, Acker, Lefkove, Arbiser, Khuri, Sun: "The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis." in: Molecular cancer therapeutics, Vol. 7, Issue 7, pp. 2212-23, (2008) (PubMed).

Chen, Liu, Yue, Schönthal, Khuri, Sun et al.: "CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of ..." in: Molecular pharmacology, Vol. 72, Issue 5, pp. 1269-79, (2007) (PubMed).

Vermot-Desroches, Sergent, Bonnin, Wijdenes: "Characterization of monoclonal antibodies directed against trail or trail receptors." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 86-91, (2005) (PubMed).

Target Details for TNFRSF10A

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Alternative Name: TRAIL R1 (TNFRSF10A Products)

Synonyms: APO2 antibody, CD261 antibody, DR4 antibody, TRAILR-1 antibody, TRAILR1 antibody, TNFRSF10A antibody, TNF receptor superfamily member 10a antibody, tumor necrosis factor receptor superfamily member 26 antibody, tumor necrosis factor receptor superfamily, member 10a antibody, TNFRSF10A antibody, LOC510798 antibody

Background: DR4, TRAIL R1

Molecular Weight: 43-46 kDa

Pathways: Apoptosis, Positive Regulation of Endopeptidase Activity