TNFRSF10B antibody

Catalog No. ABIN1383914

Product Details anti-TNFRSF10B Antibody

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF10B antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: Recognises a 42-46 kDa protein

Purification: Ion exchange chromatography

Immunogen: Recombinant human TRAIL R2/Fc chimera,Myeloma X63/AG.8653 x Balb/c spleen cells

Clone: B-K29

Isotype: IgG1 kappa

Application Details

Application Notes: Use 10 μL to label 10^6 cells or 100 μL of whole blood

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline with 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-TNFRSF10B antibody (ABIN1383914)

Ueda, Kohanbash, Sasaki, Fujita, Zhu, Kastenhuber, McDonald, Potter, Hamilton, Lotze, Khan, Sobol, Okada: "Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 26, pp. 10746-51, (2009) (PubMed).

Mérino, Lalaoui, Morizot, Schneider, Solary, Micheau: "Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2." in: Molecular and cellular biology, Vol. 26, Issue 19, pp. 7046-55, (2006) (PubMed).

Target Details for TNFRSF10B

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Alternative Name: TRAIL R2 (TNFRSF10B Products)

Synonyms: TNFRSF10B antibody, dr5 antibody, cd262 antibody, killer antibody, trick2 antibody, trickb antibody, xDR-M1 antibody, xDR-M2 antibody, ztnfr9 antibody, trailr2 antibody, trick2a antibody, trick2b antibody, CD262 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, ZTNFR9 antibody, Ly98 antibody, MK antibody, tumor necrosis factor receptor superfamily, member 10b antibody, tumor necrosis factor receptor superfamily member 10b S homeolog antibody, tumor necrosis factor receptor superfamily member 10b L homeolog antibody, tumor necrosis factor receptor superfamily member 10b antibody, TNF receptor superfamily member 10b antibody, Tnfrsf10b antibody, TNFRSF10B antibody, tnfrsf10b.S antibody, tnfrsf10b.L antibody, tnfrsf10b antibody

Background: DR5, TRAIL R2

Molecular Weight: 42-46 kDa

Pathways: p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity