Interferon gamma antibody

Catalog No. ABIN1383935

Product Details anti-Interferon gamma Antibody

Target: Interferon gamma (IFNG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Interferon gamma antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISpot, Functional Studies (Func)

Specificity: Recognises both natural and recombinant human IFN-g

Purification: Ion exchange chromatography

Sterility: 0.22 μm filtered

Immunogen: Recombinant human IFN-g,Myeloma X63/AG.8653 x Balb/c spleen cells

Clone: B-B1

Isotype: IgG1 kappa

Biological Activity Comment: Inhibits IFNγ induced proliferation

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

References for anti-Interferon gamma antibody (ABIN1383935)

Aldemir, Prodhomme, Dumaurier, Retiere, Poupon, Cazareth, Bihl, Braud: "Cutting edge: lectin-like transcript 1 is a ligand for the CD161 receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 12, pp. 7791-5, (2005) (PubMed).

Munn, Sharma, Mellor: "Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 7, pp. 4100-10, (2004) (PubMed).

Santangelo, Cousins, Winkelmann, Staynov: "DNA methylation changes at human Th2 cytokine genes coincide with DNase I hypersensitive site formation during CD4(+) T cell differentiation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 4, pp. 1893-903, (2002) (PubMed).

Cousins, Lee, Staynov: "Cytokine coexpression during human Th1/Th2 cell differentiation: direct evidence for coordinated expression of Th2 cytokines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 5, pp. 2498-506, (2002) (PubMed).

van der Loos, Houtkamp, de Boer, Teeling, van der Wal, Becker: "Immunohistochemical detection of interferon-gamma: fake or fact?" in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 49, Issue 6, pp. 699-710, (2001) (PubMed).

Yin, Siegert, Neure, Grolms, Liu, Eggens, Radbruch, Braun, Sieper: "The elevated ratio of interferon gamma-/interleukin-4-positive T cells found in synovial fluid and synovial membrane of rheumatoid arthritis patients can be changed by interleukin-4 but not by interleukin-10 or transforming growth factor beta." in: Rheumatology (Oxford, England), Vol. 38, Issue 11, pp. 1058-67, (2000) (PubMed).

Boyaka, Wright, Marinaro, Kiyono, Johnson, Gonzales, Ikizler, Werkhaven, Jackson, Fujihashi, Di Fabio, Staats, McGhee: "Human nasopharyngeal-associated lymphoreticular tissues. Functional analysis of subepithelial and intraepithelial B and T cells from adenoids and tonsils." in: The American journal of pathology, Vol. 157, Issue 6, pp. 2023-35, (2000) (PubMed).

Yeaman, Collins, Currie, Guyre, Wira, Fanger: "IFN-gamma is produced by polymorphonuclear neutrophils in human uterine endometrium and by cultured peripheral blood polymorphonuclear neutrophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 10, pp. 5145-53, (1998) (PubMed).

Roye, Delhem, Trottein, Remoué, Nutten, Decavel, Delacre, Martinot, Cesbron, Auriault, Wolowczuk: "Dermal endothelial cells and keratinocytes produce IL-7 in vivo after human Schistosoma mansoni percutaneous infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 8, pp. 4161-8, (1998) (PubMed).

Palmer, van Seventer: "Human T helper cell differentiation is regulated by the combined action of cytokines and accessory cell-dependent costimulatory signals." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 6, pp. 2654-62, (1997) (PubMed).

Fisfalen, Palmer, Van Seventer, Soltani, Sawai, Kaplan, Hidaka, Ober, DeGroot: "Thyrotropin-receptor and thyroid peroxidase-specific T cell clones and their cytokine profile in autoimmune thyroid disease." in: The Journal of clinical endocrinology and metabolism, Vol. 82, Issue 11, pp. 3655-63, (1997) (PubMed).

Picker, Singh, Zdraveski, Treer, Waldrop, Bergstresser, Maino: "Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry." in: Blood, Vol. 86, Issue 4, pp. 1408-19, (1995) (PubMed).

Target Details for Interferon gamma

Target: Interferon gamma (IFNG)

Alternative Name: IFN gamma (IFNG Products)

Synonyms: IFG antibody, IFI antibody, IFN-g antibody, Ifg antibody, IFNG2 antibody, IFN-gamma antibody, IFN-G antibody, IFNG antibody, IFNgamma antibody, TCRalpha antibody, INF-G antibody, ifng antibody, interferon gamma antibody, interferon, gamma 1-2 antibody, IFNG antibody, Ifng antibody, ifng1-2 antibody

Background: IFN-g, IFN-gamma

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy