CD40 antibody (CD40 Molecule, TNF Receptor Superfamily Member 5) (PE)

Details for Product anti-CD40 Antibody No. ABIN1384053, Supplier: Log in to see
Antigen
  • AI326936
  • Bp50
  • GP39
  • HIGM1
  • IGM
  • IMD3
  • T-BAM
  • TRAP
  • Tnfrsf5
  • p50
  • CDW40
  • TNFRSF5
  • TNFSF5
  • 2310042E05Rik
  • C130077D06Rik
  • C87049
  • DCTN-50
  • GMP23-48K
  • RBP50
  • CD40 antigen
  • CD40 molecule, TNF receptor superfamily member 5
  • dynactin 2
  • LOC100349106
  • Cd40
  • CD40
  • Dctn2
Alternatives
anti-Human CD40 antibody for Agonist
Reactivity
Human
645
312
69
20
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10
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2
1
1
1
1
Host
Mouse
506
213
166
23
6
4
Clonality (Clone)
Monoclonal ()
Conjugate
This CD40 antibody is conjugated to PE
88
84
51
24
24
21
17
15
14
13
12
9
9
9
9
9
9
9
8
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2
2
1
1
1
1
1
1
1
1
1
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1
Application
Flow Cytometry (FACS)
579
242
206
156
111
104
101
65
47
33
19
15
13
9
8
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6
4
3
3
3
3
2
2
1
1
1
1
1
1
1
Options
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Available images

Clone B-B20
Isotype IgG1
Specificity Recognises the Bp50 antigen, a 48 kDa protein
Characteristics Raji cell line.
Purification Ion exchange chromatography
Alternative Name CD40 (CD40 Antibody Abstract)
Background Myeloma X63/AG.8653 x Balb/c spleen cells
Molecular Weight 48 kDa
Research Area Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells, Apoptosis/Necrosis, Inflammation, Cancer
Pathways NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute with 1 mL deionised water
Buffer Phosphate-buffered saline with 1 % BSA and 0.1 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Use 10 µL of (diluted) antibody to label 10 6 cells or 100 µL of whole blood. Do not freeze.
Storage 4 °C
Storage Comment Declared stable after 7 days at room temperature, 6 months at +2-8°C after reconstitution. Protect from light. Do not freeze.
Expiry Date 6 months
Supplier Images
 image for anti-CD40 antibody (CD40 Molecule, TNF Receptor Superfamily Member 5)  (PE) (ABIN1384053) A typical staining pattern with the B-B20 monoclonal antibody of lymphocytes
Product cited in: Raffaghello, Nozza, Morandi, Camoriano, Wang, Garrè, Cama, Basso, Ferrone, Gambini, Pistoia: "Expression and functional analysis of human leukocyte antigen class I antigen-processing machinery in medulloblastoma." in: Cancer research, Vol. 67, Issue 11, pp. 5471-8, 2007 (PubMed).

Iwamoto, Ishida, Takahashi, Takeda, Miyazaki: "Lipopolysaccharide stimulation converts vigorously washed dendritic cells (DCs) to nonexhausted DCs expressing CD70 and evoking long-lasting type 1 T cell responses." in: Journal of leukocyte biology, Vol. 78, Issue 2, pp. 383-92, 2005 (PubMed).

Jego, Robillard, Puthier, Amiot, Accard, Pineau, Harousseau, Bataille, Pellat-Deceunynck: "Reactive plasmacytoses are expansions of plasmablasts retaining the capacity to differentiate into plasma cells." in: Blood, Vol. 94, Issue 2, pp. 701-12, 1999 (PubMed).

Kohrgruber, Halanek, Gröger, Winter, Rappersberger, Schmitt-Egenolf, Stingl, Maurer: "Survival, maturation, and function of CD11c- and CD11c+ peripheral blood dendritic cells are differentially regulated by cytokines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 6, pp. 3250-9, 1999 (PubMed).

Metcalfe, McIntosh, Marelli-Berg, Lombardi, Lechler, Weetman: "Detection of CD40 on human thyroid follicular cells: analysis of expression and function." in: The Journal of clinical endocrinology and metabolism, Vol. 83, Issue 4, pp. 1268-74, 1998 (PubMed).

Vermot-Desroches, Marchand, Roy, Wijdenes: "Heterogeneity of antigen expression among human umbilical cord vascular endothelial cells: identification of cell subsets by co-expression of haemopoietic antigens." in: Immunology letters, Vol. 48, Issue 1, pp. 1-9, 1996 (PubMed).

Background publications Iwamoto, Iwai, Tsujiyama, Kurahashi, Takeshita, Naoe, Masunaga, Ogawa, Oguchi, Miyazaki: "TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 3, pp. 1449-57, 2007 (PubMed).

Garnache-Ottou, Chaperot, Biichle, Ferrand, Remy-Martin, Deconinck, de Tailly, Bulabois, Poulet, Kuhlein, Jacob, Salaun, Arock, Drenou, Schillinger, Seilles, Tiberghien, Bensa, Plumas, Saas: "Expression of the myeloid-associated marker CD33 is not an exclusive factor for leukemic plasmacytoid dendritic cells." in: Blood, Vol. 105, Issue 3, pp. 1256-64, 2005 (PubMed).