CD86 antibody (CD86 Molecule) (PE)

Details for Product anti-CD86 Antibody No. ABIN1384057, Supplier: Log in to see
Antigen
  • B7-2
  • B7
  • B7.2
  • B70
  • CLS1
  • Cd28l2
  • ETC-1
  • Ly-58
  • Ly58
  • MB7
  • MB7-2
  • TS/A-2
  • CD28LG2
  • LAB72
  • CD86 molecule
  • CD86 antigen
  • CD86/B7-2 costimulatory molecule
  • CD86
  • Cd86
  • LOC554318
Alternatives
anti-Human CD86 antibody for Blocking Peptide
Reactivity
Human
429
380
131
14
13
10
7
3
2
2
2
Host
Mouse
364
333
94
3
Clonality (Clone)
Monoclonal ()
Conjugate
This CD86 antibody is conjugated to PE
98
95
52
32
22
21
16
15
15
13
12
9
8
8
8
8
8
8
7
6
5
5
5
4
4
4
4
4
3
2
2
2
2
2
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
632
219
167
162
102
99
85
64
58
55
14
14
13
13
12
12
8
5
3
2
2
2
2
2
1
1
1
1
Options
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Available images

Clone B-T7
Isotype IgG1
Specificity Recognises the B7.2, B70 antigen, a 80 kDa protein
Characteristics B70 transfected P815 cell line.
Purification Ion exchange chromatography
Alternative Name CD86 (CD86 Antibody Abstract)
Background Myeloma X63/AG.8653 x Balb/c spleen cells
Molecular Weight 80 kDa
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
Restrictions For Research Use only
Format Liquid
Reconstitution Reconstitute with 1 mL deionised water
Buffer Phosphate-buffered saline with 1 % BSA and 0.1 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Use 10 µL of (diluted) antibody to label 10 6 cells or 100 µL of whole blood. Do not freeze.
Storage 4 °C
Storage Comment Declared stable after 7 days at room temperature, 6 months at +2-8°C after reconstitution. Protect from light. Do not freeze.
Expiry Date 6 months
Supplier Images
 image for anti-CD86 antibody (CD86 Molecule)  (PE) (ABIN1384057) A typical staining pattern with the B-T7 monoclonal antibody of monocytes
Product cited in: Ade, Leon, Pallardy, Peiffer, Kerdine-Romer, Tissier, Bonnet, Fabre, Ourlin: "HMOX1 and NQO1 genes are upregulated in response to contact sensitizers in dendritic cells and THP-1 cell line: role of the Keap1/Nrf2 pathway." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 107, Issue 2, pp. 451-60, 2009 (PubMed).

Larangé, Antonios, Pallardy, Kerdine-Römer: "TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturation." in: Journal of leukocyte biology, Vol. 85, Issue 4, pp. 673-83, 2009 (PubMed).

Drukker, Katchman, Katz, Even-Tov Friedman, Shezen, Hornstein, Mandelboim, Reisner, Benvenisty: "Human embryonic stem cells and their differentiated derivatives are less susceptible to immune rejection than adult cells." in: Stem cells (Dayton, Ohio), Vol. 24, Issue 2, pp. 221-9, 2006 (PubMed).

Background publications Garnache-Ottou, Chaperot, Biichle, Ferrand, Remy-Martin, Deconinck, de Tailly, Bulabois, Poulet, Kuhlein, Jacob, Salaun, Arock, Drenou, Schillinger, Seilles, Tiberghien, Bensa, Plumas, Saas: "Expression of the myeloid-associated marker CD33 is not an exclusive factor for leukemic plasmacytoid dendritic cells." in: Blood, Vol. 105, Issue 3, pp. 1256-64, 2005 (PubMed).