TDRD9 antibody (AA 801-900)

Catalog No. ABIN1385847

Product Details anti-TDRD9 Antibody

Target: TDRD9 (Tudor Domain Containing 9 (TDRD9))

Binding Specificity: AA 801-900

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDRD9 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TDRD9/HIG1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TDRD9

Target: TDRD9 (Tudor Domain Containing 9 (TDRD9))

Alternative Name: TDRD9/HIG1 (TDRD9 Products)

Background:

Synonyms: C14orf75, chromosome 14 open reading frame 75, HIG 1, Hypoxia inducible HIG 1, MGC135025, Putative ATP dependent RNA helicase TDRD9, Putative ATP-dependent RNA helicase TDRD9, TDRD 9, Tdrd9, TDRD9_HUMAN , Tudor domain containing 9, Tudor domain containing protein 9, Tudor domain-containing protein 9.

Background: Probable ATP-binding RNA helicase which plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with PIWIL4 and the piP-bodies suggests a participation in the secondary piRNAs metabolic process.

Gene ID: 122402