TPM1/2/3/4 (AA 210-260) antibody
Reactivity: Human, Mouse, Rat
IF (p), IHC (p), WB
Host: Rabbit
Polyclonal
unconjugated
-
- Target
- TPM1/2/3/4
- Binding Specificity
- AA 210-260
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
- Specificity
- This antibody will detect all 4 Tropomyosin proteins: TPM1, TPM2, TPM3, and TPM4
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TPM1
- Isotype
- IgG
-
- Application Notes
-
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
-
- Target
- TPM1/2/3/4
- Background
-
Synonyms: TPM1, Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1, C15orf13, TMSA, TPM2, Tropomyosin beta chain, Beta-tropomyosin, Tropomyosin-2, TMSB, TPM3, Tropomyosin alpha-3 chain, Gamma-tropomyosin, Tropomyosin-3, TPM4, Tropomyosin alpha-4 chain, TM30p1, Tropomyosin-4
Background: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
- Gene ID
- 7168
- UniProt
- P09493
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