PVRL1 antibody (AA 31-130)

Catalog No. ABIN1387462

Product Details anti-PVRL1 Antibody

Target: PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))

Binding Specificity: AA 31-130

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PVRL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD111/Nectin1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
dot-blot()
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PVRL1

Target: PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))

Alternative Name: CD111/Nectin1 (PVRL1 Products)

Synonyms: CD111 antibody, CLPED1 antibody, ED4 antibody, HIgR antibody, HVEC antibody, OFC7 antibody, PRR antibody, PRR1 antibody, PVRR antibody, PVRR1 antibody, SK-12 antibody, nectin-1 antibody, prr1 antibody, PVRL1 antibody, pvrl1 antibody, AI835281 antibody, AW549174 antibody, Cd111 antibody, HveC antibody, cd111 antibody, cd112 antibody, clped1 antibody, ed4 antibody, higr antibody, hveb antibody, hvec antibody, nectin-2 antibody, ofc7 antibody, prr antibody, prr2 antibody, pvrl2 antibody, pvrl2.L antibody, pvrr antibody, pvrr1 antibody, pvrr2 antibody, sk-12 antibody, nectin cell adhesion molecule 1 antibody, nectin-1 antibody, Poliovirus receptor-related protein 1 antibody, poliovirus receptor-related 1 (herpesvirus entry mediator C) antibody, nectin cell adhesion molecule 2 L homeolog antibody, NECTIN1 antibody, LOC100145553 antibody, pvrl1 antibody, nectin1 antibody, Nectin1 antibody, PVRL1 antibody, nectin2.L antibody

Background:

Synonyms: ED4, PRR, HIgR, HV1S, HVEC, OFC7, PRR1, PVRR, CD111, PVRR1, SK-12, CLPED1, nectin-1, Herpes virus entry mediator C, Herpesvirus entry mediator C, Herpesvirus Ig-like receptor, Poliovirus receptor-related protein 1, PVRL1

Background: Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between PVRL1/nectin-1 and PVRL3/nectin-3 and between PVRL1/nectin-1 and PVRL4/nectin-4. Functions as an entry receptor for herpes simplex virus and pseudorabies virus. Has some neurite outgrowth-promoting activity.

Gene ID: 5818

UniProt: Q15223

Pathways: Cell-Cell Junction Organization