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Sulfiredoxin 1 antibody (AA 45-137)

SRX1 Reactivity: Human, Mouse, Rat WB, ELISA, IF (p), IF (cc), IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387599
  • Target See all Sulfiredoxin 1 (SRX1) Antibodies
    Sulfiredoxin 1 (SRX1)
    Binding Specificity
    • 14
    • 1
    AA 45-137
    Reactivity
    Human, Mouse, Rat
    Host
    • 16
    • 1
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Sulfiredoxin 1 antibody is un-conjugated
    Application
    • 17
    • 12
    • 12
    • 5
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SRXN1
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Zhang, He, Guo, Li, Wang, Yang, Cui: "Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways." in: Bioscience reports, Vol. 36, Issue 2, (2016) (PubMed).

    Zhou, Zhou, Yu, Wu, Chen, Zhao et al.: "Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen ..." in: International journal of molecular medicine, Vol. 36, Issue 1, pp. 43-52, (2015) (PubMed).

  • Target
    Sulfiredoxin 1 (SRX1)
    Alternative Name
    SRXN1 (SRX1 Products)
    Synonyms
    C20orf139 antibody, Npn3 antibody, SRX antibody, SRX1 antibody, Ab2-390 antibody, 1700127B04Rik antibody, AI854065 antibody, AW488194 antibody, Srx antibody, Srx1 antibody, TX01 antibody, sulfiredoxin 1 antibody, sulfiredoxin 1 homolog (S. cerevisiae) antibody, SRXN1 antibody, srxn1 antibody, Srxn1 antibody
    Background

    Synonyms: SRX, Npn3, SRX1, C20orf139, Sulfiredoxin-1, SRXN1

    Background: Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.

    Gene ID
    140809
    UniProt
    Q9BYN0
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