DOK5 antibody (AA 21-120)

Catalog No. ABIN1387610

Product Details anti-DOK5 Antibody

Target: DOK5 (Docking Protein 5 (DOK5))

Binding Specificity: AA 21-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DOK5/IRS6

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-DOK5 antibody (ABIN1387610)

Pan, Zhang, Liu, Shu, Yin, Yuan, Qiang, Peng: "Dok5 is involved in the signaling pathway of neurotrophin-3 against TrkC-induced apoptosis." in: Neuroscience letters, Vol. 553, pp. 46-51, (2013) (PubMed).

Target Details for DOK5

Target: DOK5 (Docking Protein 5 (DOK5))

Alternative Name: DOK5 (DOK5 Products)

Synonyms: C20orf180 antibody, 2700055C10Rik antibody, RGD1562846 antibody, docking protein 5 antibody, Docking protein 5 antibody, DOK5 antibody, dok5 antibody, Dok5 antibody

Background:

Synonyms: IRS6, IRS-6, C2orf18, Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, DOK5

Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.

Gene ID: 55816

UniProt: Q9P104