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BFSP2 antibody (AA 181-280) (Alexa Fluor 488)

BFSP2 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 488
Catalog No. ABIN1388776
  • Target See all BFSP2 Antibodies
    BFSP2 (Beaded Filament Structural Protein 2, Phakinin (BFSP2))
    Binding Specificity
    • 14
    • 4
    • 2
    • 1
    • 1
    AA 181-280
    Reactivity
    • 23
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 22
    • 3
    Rabbit
    Clonality
    • 22
    • 3
    Polyclonal
    Conjugate
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BFSP2 antibody is conjugated to Alexa Fluor 488
    Application
    • 22
    • 12
    • 12
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human BFSP2/Phakinin
    Isotype
    IgG
    Top Product
    Discover our top product BFSP2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    BFSP2 (Beaded Filament Structural Protein 2, Phakinin (BFSP2))
    Alternative Name
    Bfsp2/Phakinin (BFSP2 Products)
    Synonyms
    CP47 antibody, CP49 antibody, CTRCT12 antibody, LIFL-L antibody, PHAKOSIN antibody, AI448593 antibody, CP49INS antibody, BFSP2 antibody, LOC100222605 antibody, Bfsp2 antibody, zgc:103750 antibody, beaded filament structural protein 2 antibody, beaded filament structural protein 2, phakinin antibody, BFSP2 antibody, Bfsp2 antibody, bfsp2 antibody
    Background

    Synonyms: 49 kDa cytoskeletal protein, Beaded filament protein CP49, Beaded filament structural protein 2, Beaded filament structural protein 2, phakinin, Bfps2, Cytoskeletal protein, 49 kD, BFSP2, BFSP2_HUMAN, CP47, CP49, Lens fiber cell beaded filament protein CP 47, Lens fiber cell beaded filament protein CP 49,Lens intermediate filament-like light, LL-L, Phakinin, PHAKOSIN.

    Background: Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10-nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.

    Gene ID
    3921
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