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FAT3 antibody (AA 601-800) (Alexa Fluor 350)

FAT3 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 350
Catalog No. ABIN1389153
  • Target See all FAT3 Antibodies
    FAT3 (FAT Tumor Suppressor Homolog 3 (FAT3))
    Binding Specificity
    • 14
    • 5
    AA 601-800
    Reactivity
    • 20
    • 1
    • 1
    Human
    Host
    • 20
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAT3 antibody is conjugated to Alexa Fluor 350
    Application
    • 12
    • 12
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CDHF15/FAT3
    Isotype
    IgG
    Top Product
    Discover our top product FAT3 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    FAT3 (FAT Tumor Suppressor Homolog 3 (FAT3))
    Alternative Name
    CDHF15/FAT3 (FAT3 Products)
    Synonyms
    CDHF15 antibody, CDHR10 antibody, 9430076A06Rik antibody, D430038H04Rik antibody, Gm1132 antibody, Gm510 antibody, MFAT3F antibody, FAT atypical cadherin 3 antibody, FAT3 antibody, Fat3 antibody
    Background

    Synonyms: Cadherin family member 15, CDHF15, CDHR10, FAT tumor suppressor homolog 3, Fat3, FAT3_HUMAN, hFat3, Protocadherin Fat 3.

    Background: The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including -catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT3 (FAT tumor suppressor homolog 3, also known as CDHF15 or CDHR10, is a 4,589 amino acid single-pass type I membrane protein expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate. Containing thirty-three cadherin domains, four EGF-like domains and one laminin G-like domain, FAT3 may participate in the interactions between neurites derived from specific subsets of neurons during development.

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