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HSC70 Interacting Protein HIP antibody (AA 181-280) (FITC)

ST13 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal FITC
Catalog No. ABIN1390280
  • Target See all HSC70 Interacting Protein HIP (ST13) Antibodies
    HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))
    Binding Specificity
    • 14
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 181-280
    Reactivity
    • 44
    • 16
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 36
    • 9
    Rabbit
    Clonality
    • 37
    • 8
    Polyclonal
    Conjugate
    • 27
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HSC70 Interacting Protein HIP antibody is conjugated to FITC
    Application
    • 44
    • 17
    • 12
    • 12
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HSPABP
    Isotype
    IgG
    Top Product
    Discover our top product ST13 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))
    Alternative Name
    ST13 (ST13 Products)
    Synonyms
    CG32789 antibody, Dmel\\CG32789 antibody, anon-EST:fe1A9 antibody, 1110007I03Rik antibody, 3110002K08Rik antibody, AW555194 antibody, HIP antibody, HOP antibody, HSPABP antibody, HSPABP1 antibody, PRO0786 antibody, SNC6 antibody, p48 antibody, AAG2 antibody, FAM10A1 antibody, FAM10A4 antibody, P48 antibody, Hsc/Hsp70-interacting protein antibody, suppression of tumorigenicity 13 antibody, ST13, Hsp70 interacting protein antibody, suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) antibody, HIP antibody, St13 antibody, ST13 antibody
    Background

    Synonyms: AAG 2, AAG2, Aging associated protein 2, F10A1_HUMAN, FAM10A1, FAM10A4, FLJ27260, Heat shock 70kD protein binding protein, HIP, HOP, Hsc70 interacting protein, Hsc70-interacting protein, Hsp70 interacting protein, HSPABP 1, HSPABP, HSPABP1, MGC129952, OTTHUMP00000028873, P48 antibody PRO0786, Progesterone receptor associated p48 protein, Progesterone receptor-associated p48 protein, Protein FAM10A1, Putative tumor suppressor ST13, Renal carcinoma antigen NY REN 33, Renal carcinoma antigen NY-REN-33, SNC 6, SNC6, ST 13, ST13, Suppression of tumorigenicity 13, Suppression of tumorigenicity 13 colon carcinoma, Suppression of tumorigenicity 13 protein, Suppression of tumorigenicity protein 13.

    Background: Hip (HSP70-interacting protein), also known as ST13 (suppression of tumorigenicity protein 13), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1,2). The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3). By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8).

    Gene ID
    6767
    UniProt
    P50502
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